Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair
about
Spartan/C1orf124 is important to prevent UV-induced mutagenesisA ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair networkMolecular pathogenesis and clinical management of Fanconi anemiaHow SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair PathwayExploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapyStructure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage responseStructural insights into the functions of the FANCM-FAAP24 complex in DNA repairBiophysical characterization of the interaction between FAAP20-UBZ4 domain and Rev1-BRCT domainForkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage responseAdvances in understanding the complex mechanisms of DNA interstrand cross-link repairAluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.The genetic and biochemical basis of FANCD2 monoubiquitinationRegulation of DNA cross-link repair by the Fanconi anemia/BRCA pathwayC. elegans ring finger protein RNF-113 is involved in interstrand DNA crosslink repair and interacts with a RAD51C homolog.Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain.RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway.Defective FANCI binding by a fanconi anemia-related FANCD2 mutant.Structural basis for ubiquitin recognition by ubiquitin-binding zinc finger of FAAP20.Human FAN1 promotes strand incision in 5'-flapped DNA complexed with RPA.Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress.FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex.Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein.Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress.FANCM and FAAP24 maintain genome stability via cooperative as well as unique functionsThe Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma.MTE1 Functions with MPH1 in Double-Strand Break Repair.Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinksThe Fanconi anemia pathway in replication stress and DNA crosslink repair.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Stress and DNA repair biology of the Fanconi anemia pathwayFanconi anaemia: genetics, molecular biology, and cancer – implications for clinical management in children and adults.Ubiquitin-like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway.Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases.Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair.Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia.FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation.FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers.Modularized functions of the Fanconi anemia core complex.ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.
P2860
Q24296499-0041A926-7F45-42D2-96B8-8AB6B02C0529Q24338452-37251124-12E6-420A-A9A2-AD7BFEB5EEB8Q24621696-7353FBF8-5139-48F0-BC96-BAD6183A663AQ26752451-3C21D24B-45C8-4D42-B1CE-12FFBD1B997BQ26801593-C58B9CCD-236B-43AB-923A-6BA26B5056EBQ27679861-7BE5C56B-E8D5-40D5-A887-226659A413C9Q27679863-D7683C10-37BE-4250-AE9E-0645D2DD20ECQ28115633-8F1D62A2-E6BE-4C57-A34D-83A1FB644923Q28270475-6AFBFBE2-0979-46A6-9E2A-EC3BED592C8FQ28299636-6C02DFDD-D683-4E85-BC43-AB1CECC1FC20Q30371243-F5C40E81-0D2E-4668-A486-498B39D28D40Q33735561-3DD7D2D0-6DCF-4065-9BCC-AC7B9BE543CEQ34285356-A641EC8E-67CE-45E3-B911-5F1286313FEEQ34337102-FE0CDB6E-AE29-44F0-952B-60E804F3407FQ34711904-1BE5B064-165A-4263-8854-12C852D74918Q35409078-DCA47A81-CBE6-4213-8348-CFC52BF62A24Q35502827-672FEAD9-296D-43CE-A4BE-17E493DBF700Q35583928-32BDCF77-2F3E-4B2F-8A59-D716586229FFQ35617226-B5A35C08-07B5-4643-9FC3-4FF884EA2541Q35772723-FE40394A-CDA8-458A-BFC7-5E56BF3403EDQ36187965-A172387A-4CF5-4839-B362-125F2AC29ABEQ36220736-3092BFF5-C641-40B9-A1A6-DAFA3EF28664Q36647310-5F8BC1E1-3DEF-4398-BA43-BFA2F499D48CQ36677983-57F97276-6DCA-4A79-A60E-1818F30F33F1Q36867985-9575C96E-BC4A-43A6-B9C6-8D1662AA74AFQ36875579-7ECDD059-6B26-48EB-B5F5-06727ACEF2C8Q37516257-1358C3BA-8FA6-40B5-A7D6-120021C875EFQ38022544-3FDD8FB2-0EA5-4F3D-872B-C4B9F0EC802AQ38052100-A2A8C750-C676-46F7-93B2-35DDAEA321EDQ38063711-6710A27B-8A27-4225-A7D2-A3C8ED6F80EEQ38252562-C5776944-B132-4893-8808-1BA9390564B2Q38259296-389CED18-8648-4B8C-A79B-48087642BE4FQ38888704-B04D04D9-5099-4F5E-B211-3160CBD0A473Q38937471-305E6345-091E-4F01-A5C8-ED6733BCD940Q39308806-00FBBFF0-146C-4DAD-8C6E-E3E6669B4F25Q41482346-5D303846-0259-47BC-96EF-70851F2D8B51Q41667106-8EDDB349-F27B-4EF7-BCC8-3F35BCE1E71CQ41828543-AF959D24-021E-4920-9391-A0B7C3C0A7E2Q41915735-74811CC7-3DBD-4E83-91DB-43386A3AE6F2Q41967452-39D275C8-4D0F-45A0-B5C2-929F8FAE4B4B
P2860
Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@ast
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@en
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@en-gb
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@nl
type
label
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@ast
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@en
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@en-gb
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@nl
prefLabel
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@ast
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@en
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@en-gb
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@nl
P2093
P2860
P3181
P356
P1476
Fanconi anemia (FA) binding pr ...... interstrand cross-link repair
@en
P2093
Junjie Chen
Justin Wai Chung Leung
Michael Shing Yan Huen
Yucai Wang
P2860
P304
P3181
P356
10.1073/PNAS.1118720109
P407
P50
P577
2012-03-20T00:00:00Z