%D8%AF%D9%8A%D9%81%D9%8A%D8%AF_%D8%A3%D9%86%D8%AF%D8%B1%D9%88_%D8%B3%D9%86%D9%83%D9%84%D9%8A%D8%B1David_A._SinclairDavid_Andrew_Sinclair%D7%93%D7%99%D7%99%D7%95%D7%95%D7%99%D7%93_%D7%A1%D7%99%D7%A0%D7%A7%D7%9C%D7%99%D7%99%D7%A8%D0%94%D1%8D%D0%B2%D0%B8%D0%B4_%D0%AD%D0%BD%D0%B4%D1%80%D1%8E_%D0%A1%D0%B8%D0%BD%D0%BA%D0%BB%D0%B5%D1%80David_Andrew_SinclairQ5239823%E5%A4%A7%E8%A1%9B%C2%B7%E5%AE%89%E5%BE%B7%E9%AD%AF%C2%B7%E8%BE%9B%E5%85%8B%E8%90%8A
about
P1037
Mosquito larval source management for controlling malariaDrugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatmentGuidelines for the use and interpretation of assays for monitoring autophagyCalorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylaseSIRT2 induces the checkpoint kinase BubR1 to increase lifespanStress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylaseA high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complexSir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signalingSIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during agingRapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous miceEvaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous miceNutrient-sensitive mitochondrial NAD+ levels dictate cell survivalSRT1720 improves survival and healthspan of obese miceSmall molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetesResveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life spanWhen stem cells grow old: phenotypes and mechanisms of stem cell agingSirtuin 1 and sirtuin 3: physiological modulators of metabolismResveratrol improves health and survival of mice on a high-calorie dietRedistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatinNQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.HST2 mediates SIR2-independent life-span extension by calorie restriction.Role of the N-terminal region of Rap1p in the transcriptional activation of glycolytic genes in Saccharomyces cerevisiae.MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaksSmall molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanInhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1Small molecules that regulate lifespan: evidence for xenohormesisThe role of protein arginine methylation in the formation of silent chromatinEvidence for a common mechanism of SIRT1 regulation by allosteric activatorsDeclining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during agingBiochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3Prolyl isomerase Pin1 regulates neuronal differentiation via β-cateninSynthesis and Assay of SIRT1-Activating CompoundsTherapeutic potential of resveratrol: the in vivo evidenceSirtuin activators mimic caloric restriction and delay ageing in metazoansExtrachromosomal rDNA circles--a cause of aging in yeastGLTSCR2/PICT1 links mitochondrial stress and Myc signaling.
P50
P5769
Q21032514-E013D052-54EE-411A-8100-DAA97A15B3EEQ21032529-4E21B5A4-B49F-4396-AC42-2017F2A6E7ABQ21996341-C23B14AE-D295-483A-90D4-79DBE4416004Q24297207-6E45537E-B763-4F98-B12E-A0710E1F75AFQ24297676-1575B455-D8C9-4719-98EB-020A7230BEF1Q24310456-B38E8017-3809-4EEE-901F-D2D2F9E18250Q24314096-3DAE5442-DACB-4FDA-944D-B28E965D024EQ24338727-B088BFE1-DB60-48BE-A985-141927D165BEQ24595900-EB96776D-477B-418F-957F-20813C147E0EQ24597354-B892CE34-E0CD-4E19-BAC3-748512ECAC7FQ24604312-86C3F23E-CCEA-4A8E-9F51-C9CB37578DFDQ24612868-DC889584-1BA4-4359-B218-321EFC4FA828Q24627930-E1AB7E2A-B4B7-4FFB-AA8B-6470D1A659F3Q24645537-B1DCE7B0-3194-4732-8682-C4550F309DB3Q24649811-4F6CB5D5-2360-40EF-81E5-FB13BA7D12EFQ26770845-D3973255-68D4-48A1-9541-4E19453620C1Q26828607-8B566B40-0EC4-4916-9A84-3AB987DDF44DQ27860950-2FA53846-DAAE-4003-B886-7C606B87123FQ27931333-757D3D90-DA93-4FC8-874E-5DED8FDC8833Q27931494-4C6F53E1-F551-42D0-AFF8-A499B5360C32Q27931533-3D4C6B94-03E0-48CF-B489-D32DD85319FDQ27932205-9F8D4BC7-2D0C-4173-9C26-FEAA2D221E8EQ27932823-76FB6474-6C44-4B74-99EA-36EF93C2C600Q27933382-7136BCC3-4E07-4CC6-A677-07CF4B7DA762Q27934847-70A0D582-EF67-4058-B16A-2F91E9C9694EQ27935954-2A0CAC5E-DC9E-4FA0-BDA6-C81FA5FA30C6Q28137625-6A6F322B-89DE-452E-AB07-E2F071161286Q28203572-54DDD162-59EF-4DDD-BBD5-5D94DCB5FFA4Q28203762-D55E17AD-1702-44BD-A16E-7796EA0EC4E8Q28276642-6E0534D2-E76F-4511-9EE4-C304741ED6C7Q28278117-0A1A0540-569F-46B0-9F79-661333F9BEC6Q28286859-521AE6C0-FD13-4090-A3F7-31296D8E0715Q28304473-F3FC7298-C69A-4A1C-BCB1-93323ED1872DQ28512747-A5017529-C61B-4A93-A29F-78F9D54C7D56Q28586339-2842DAD9-27BE-4C7D-A5E1-20C7E32368CFQ28818352-E985D3FA-8FD3-4FD8-A1ED-B312E99F5B38Q29547413-1E4BA0A7-D024-4D31-90B1-57E17E2C8B8EQ29547766-D1F719A5-A2E2-44CC-B603-6CEFCA9A2745Q29618308-6DC15966-459E-46B0-A61E-CC45D8174B87Q29871472-22831E12-79D9-454C-BB65-B6CABA2BE2C7
P50
description
Australian biologist and geneticist
@en
Australisch bioloog, geneticus
@nl
ahli biologi asal Australia
@id
australischer Biologe und Altersforscher
@de
genetista australiano
@it
ביולוג וגנטיקאי אוסטרלי
@he
name
David A. Sinclair
@de
David A. Sinclair
@de-ch
David Sinclair
@ace
David Sinclair
@af
David Sinclair
@ast
David Sinclair
@ca
David Sinclair
@da
David Sinclair
@en
David Sinclair
@en-ca
David Sinclair
@en-gb
type
label
David A. Sinclair
@de
David A. Sinclair
@de-ch
David Sinclair
@ace
David Sinclair
@af
David Sinclair
@ast
David Sinclair
@ca
David Sinclair
@da
David Sinclair
@en
David Sinclair
@en-ca
David Sinclair
@en-gb
altLabel
David A. Sinclair
@en
David Andrew Sinclair
@en
prefLabel
David A. Sinclair
@de
David A. Sinclair
@de-ch
David Sinclair
@ace
David Sinclair
@af
David Sinclair
@ast
David Sinclair
@ca
David Sinclair
@da
David Sinclair
@en
David Sinclair
@en-ca
David Sinclair
@en-gb
P106
P244
P1153
7202616850
P1416
P19
P1960
lfLudSQAAAAJ
P2002
davidasinclair
P2003
davidsinclairphd
P2013
davidsinclairphd