Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
about
Identification of a TPX2-like microtubule-associated protein in DrosophilaInvolvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genesModulation of kinase-inhibitor interactions by auxiliary protein binding: crystallography studies on Aurora A interactions with VX-680 and with TPX2Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora APlk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBoraA cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing MicrotubulesAnaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exitSolution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinaseTPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindleSpindle pole regulation by a discrete Eg5-interacting domain in TPX2The mechanism of spindle assembly: functions of Ran and its target TPX2Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionUbiquitin-Mediated Degradation of Aurora KinasesCross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle AssemblyAurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A ReviewAbscisic acid perception and signaling: structural mechanisms and applicationsThe Renaissance or the cuckoo clockAurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindleThe KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegansA Cell Biologist's Field Guide to Aurora Kinase InhibitorsAurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle AssemblySpatial Compartmentalization Specializes the Function of Aurora A and Aurora B.Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module.TPX2 Inhibits Eg5 by Interactions with Both Motor and Microtubule.Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathwaysTwo TPX2-dependent switches control the activity of Aurora AMeiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytesCrystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125Insights into the Conformational Variability and Regulation of Human Nek2 KinaseStructure and functional characterization of the atypical human kinase haspinAn Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug designTurning a protein kinase on or off from a single allosteric site via disulfide trapping.Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1Crystal Structure of Human Aurora B in Complex with INCENP and VX-680Optimization of Imidazo[4,5- b ]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid LeukemiaSelective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity ScreenStructural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases
P2860
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P2860
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@ast
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@en
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@en-gb
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@nl
type
label
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@ast
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@en
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@en-gb
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@nl
prefLabel
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@ast
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@en
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@en-gb
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@nl
P50
P921
P3181
P1433
P1476
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle
@en
P2093
Teresa Sardon
P304
P3181
P356
10.1016/S1097-2765(03)00392-7
P407
P577
2003-10-01T00:00:00Z