about
A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signalingChibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathwayDisruptive CHD8 mutations define a subtype of autism early in developmentTC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of ChibbyMolecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machineryMutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerizationMutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathyDisrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signalingThe TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling.Inhibition of Tcf3 binding by I-mfa domain proteinsWnt signaling promotes hematoendothelial cell development from human embryonic stem cellsChibby promotes adipocyte differentiation through inhibition of beta-catenin signalingEstablishment of the dorsal-ventral axis in Xenopus embryos coincides with the dorsal enrichment of dishevelled that is dependent on cortical rotationA plasmid-based system for expressing small interfering RNA libraries in mammalian cellsWnt signaling induces epithelial differentiation during cutaneous wound healingBili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formationCrystal Structure of a Full-Length β-CateninCrystal structures of the extracellular domain of LRP6 and its complex with DKK1Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitmentThe tuberin-hamartin complex negatively regulates beta-catenin signaling activityGenetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regenerationTC1(C8orf4) correlates with Wnt/beta-catenin target genes and aggressive biological behavior in gastric cancerThe KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradationWIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signalingCanonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neuronsActivation of rat frizzled-1 promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via pathways that require Galpha(q) and Galpha(o) functionSignaling of rat Frizzled-2 through phosphodiesterase and cyclic GMPWnt-beta-catenin signaling initiates taste papilla developmentProtein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent mannerCa(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in XenopusThe Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shapeWNT signalling pathways as therapeutic targets in cancerProximal events in Wnt signal transductionMicrofluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells.Macrophages modulate adult zebrafish tail fin regeneration.Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling.The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.Zebrafish mdk2, a novel secreted midkine, participates in posterior neurogenesis.Small-molecule synergist of the Wnt/beta-catenin signaling pathway.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Randall T Moon
@es
Randall T. Moon
@en
Randall T. Moon
@nl
Randall T. Moon
@sl
type
label
Randall T Moon
@es
Randall T. Moon
@en
Randall T. Moon
@nl
Randall T. Moon
@sl
prefLabel
Randall T Moon
@es
Randall T. Moon
@en
Randall T. Moon
@nl
Randall T. Moon
@sl
P1053
B-1743-2014
P106
P1153
7202316413
P21
P31
P3829
P496
0000-0002-9352-1408
P569
2000-01-01T00:00:00Z