Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase.
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Embryonic poly(A)-binding protein stimulates translation in germ cellsStructural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding proteinTwo PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencingMolecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding proteinPhosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fateMammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylationPoly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding proteinPoly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decayQuantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulationCytoplasmic poly(A) binding proteins regulate telomerase activity and cell growth in human papillomavirus type 16 E6-expressing keratinocytesNFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cellsHuman TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylationStructural insights into the human GW182-PABC interaction in microRNA-mediated deadenylationLa-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA StabilityA specific role for the C-terminal region of the Poly(A)-binding protein in mRNA decayThe putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylationComparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD functionHECT E3s and human disease.Poly(A) binding proteins: are they all created equal?The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay.A novel transcription factor, ERD15 (Early Responsive to Dehydration 15), connects endoplasmic reticulum stress with an osmotic stress-induced cell death signal.Makorin ring zinc finger protein 1 (MKRN1), a novel poly(A)-binding protein-interacting protein, stimulates translation in nerve cells.The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities.The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.Biological role of the two overlapping poly(A)-binding protein interacting motifs 2 (PAM2) of eukaryotic releasing factor eRF3 in mRNA decay.Studies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility.Microtubule-dependent mRNA transport in fungi.Viral subversion of host functions for picornavirus translation and RNA replication.Stress granules and cell signaling: more than just a passing phase?Modulation of enteroviral proteinase cleavage of poly(A)-binding protein (PABP) by conformation and PABP-associated factorsEARLY RESPONSIVE TO DEHYDRATION 15, a negative regulator of abscisic acid responses in Arabidopsis.The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1Rubella virus capsid protein interacts with poly(a)-binding protein and inhibits translation.A FYVE zinc finger domain protein specifically links mRNA transport to endosome trafficking.Cleavage of poly(A)-binding protein by poliovirus 3C proteinase inhibits viral internal ribosome entry site-mediated translationGTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding.Harnessing short poly(A)-binding protein-interacting peptides for the suppression of nonsense-mediated mRNA decay.Crystallization and preliminary X-ray diffraction analysis of the middle domain of Paip1.Herpes simplex virus proteins ICP27 and UL47 associate with polyadenylate-binding protein and control its subcellular distribution.
P2860
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P2860
Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structural basis of ligand rec ...... in and a HECT ubiquitin ligase
@nl
Structural basis of ligand rec ...... n and a HECT ubiquitin ligase.
@ast
Structural basis of ligand rec ...... n and a HECT ubiquitin ligase.
@en
type
label
Structural basis of ligand rec ...... in and a HECT ubiquitin ligase
@nl
Structural basis of ligand rec ...... n and a HECT ubiquitin ligase.
@ast
Structural basis of ligand rec ...... n and a HECT ubiquitin ligase.
@en
prefLabel
Structural basis of ligand rec ...... in and a HECT ubiquitin ligase
@nl
Structural basis of ligand rec ...... n and a HECT ubiquitin ligase.
@ast
Structural basis of ligand rec ...... n and a HECT ubiquitin ligase.
@en
P2093
P2860
P50
P356
P1433
P1476
Structural basis of ligand rec ...... n and a HECT ubiquitin ligase.
@en
P2093
Avak Kahvejian
Daniel Fantus
Demetra Elias
Gregory De Crescenzo
Irena Ekiel
Jean-François Trempe
Maureen O'Connor-McCourt
Nadeem Siddiqui
Nadia S Lim
P2860
P304
P356
10.1038/SJ.EMBOJ.7600048
P407
P577
2003-12-18T00:00:00Z