Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
about
Drugging the Cancers Addicted to DNA Repair.The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2.Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication.The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways.Involvement of FANCD2 in Energy Metabolism via ATP5α.FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation.BRCA1 alterations with additional defects in DNA damage response genes may confer chemoresistance to BRCA-like breast cancers treated with neoadjuvant chemotherapy.
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Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
description
2015 nî lūn-bûn
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2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
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2015年论文
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name
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@ast
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@en
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@nl
type
label
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@ast
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@en
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@nl
prefLabel
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@ast
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@en
Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@nl
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Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
@en
P2093
Hyungjin Kim
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P304
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P356
10.14348/MOLCELLS.2015.0175
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2015-08-01T00:00:00Z