Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
about
Different quaternary structures of human RECQ1 are associated with its dual enzymatic activityRECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progressionStructural and functional analyses of disease-causing missense mutations in Bloom syndrome proteinStimulation of flap endonuclease-1 by the Bloom's syndrome proteinPhysical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicasesPhysical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factorsHuman RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptideAnalysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein AHuman RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication forkSrs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa.Structural and functional characterizations reveal the importance of a zinc binding domain in Bloom's syndrome helicaseThe Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNAG-quadruplexes and helicasesDisease-causing missense mutations in human DNA helicase disordersHigh-resolution structure of the E.coli RecQ helicase catalytic coreCrystal structure of the HRDC domain of human Werner syndrome protein, WRNStructure and function of the regulatory HRDC domain from human Bloom syndrome proteinStructure of human Bloom's syndrome helicase in complex with ADP and duplex DNAMobility in the structure of E.coli recQ helicase upon substrate binding as seen from molecular dynamics simulations.Does BLM helicase unwind nucleosomal DNA?RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicasesCrystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changesHuman RECQL5beta stimulates flap endonuclease 1Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivityJunction of RecQ helicase biochemistry and human disease.DNA end resection controls the balance between homologous and illegitimate recombination in Escherichia coli.RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATPThe dissolution of double Holliday junctions.Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structuresSgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase.Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand.Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.Structure and function of RecQ DNA helicases.ATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity.RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins.DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion.Human RecQ helicases in DNA repair, recombination, and replication.DNA binding residues in the RQC domain of Werner protein are critical for its catalytic activities.
P2860
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P2860
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@ast
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@en
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@en-gb
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@nl
type
label
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@ast
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@en
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@en-gb
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@nl
prefLabel
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@ast
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@en
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@en-gb
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@nl
P2093
P3181
P1476
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein
@en
P2093
Fabienne Hamburger
Hideo Ikeda
Kouya Shiraishi
Patrick L Garcia
Pavel Janscak
Thomas A Bickle
Yoko Makuta
Yukiho Imai
P3181
P356
10.1016/S0022-2836(03)00534-5
P407
P577
2003-06-27T00:00:00Z