Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes
about
Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.Cellular defects caused by hypomorphic variants of the Bloom syndrome helicase gene BLM.Mechanistic insight into cadmium-induced inactivation of the Bloom protein.Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination.Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding.The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism.Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions.Helicase Stepping Investigated with One-Nucleotide Resolution Fluorescence Resonance Energy Transfer.The experimental analysis of mimivirus translation initiation factor 4a reveals its importance for viral proteins translation during infection of Acanthamoeba polyphaga.Purification and enzymatic characterization of Gallus gallus BLM helicase.Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.New Insights Into DNA Helicases as Druggable Targets for Cancer TherapySingle molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSBThe universally conserved GTPase HflX is an RNA helicase that restores heat-damaged ribosomes
P2860
Q29871515-B9AED4E5-FEF4-4B79-BE9F-ECFD8557B9C5Q36447371-63B1C018-A34F-4941-923D-C853F330BB2AQ36914678-B79E5694-436B-46D2-A785-B6DEBF9BD401Q37612588-FCF6C7A9-D2EE-42F0-869D-BFE6115FCCA5Q37683828-806B68AF-964A-4A41-8979-EB5DF2FA08CFQ41006842-E0BA4AB1-CD3F-41CB-9E42-6E710C81994EQ42291026-A57C623C-76A8-4C6D-8279-60D4F0C93011Q47259551-D5228576-2CA0-44B6-8FC1-96BEA33F2B39Q50005019-1E9E5002-1487-4F8D-B155-3B95510447E8Q50420475-A2127BA3-FC9B-4E9F-B93A-D0514551064DQ51088270-90885A75-05AB-4BC2-BF23-08458F6CAF69Q52607320-21C7426D-3083-448C-A730-20547377B0F3Q56476152-FBF7FF89-9DAD-4F75-B041-21F88DA329FAQ57752932-8EA485F7-4B5B-42E6-8899-0D5D64865445Q57753732-CB67F125-00A6-4CD2-BE8B-F50EDEFE223C
P2860
Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Crystal structure of the Bloom ...... main in conformational changes
@ast
Crystal structure of the Bloom ...... main in conformational changes
@en
type
label
Crystal structure of the Bloom ...... main in conformational changes
@ast
Crystal structure of the Bloom ...... main in conformational changes
@en
prefLabel
Crystal structure of the Bloom ...... main in conformational changes
@ast
Crystal structure of the Bloom ...... main in conformational changes
@en
P2093
P2860
P50
P921
P356
P1476
Crystal structure of the Bloom ...... main in conformational changes
@en
P2093
Charles K Allerston
Els Pardon
Ian D Hickson
Kata Sarlós
Pavel Savitsky
Özgün Özer
P2860
P304
P356
10.1093/NAR/GKV373
P407
P577
2015-04-21T00:00:00Z