Human RecQ helicases in DNA repair, recombination, and replication.
about
Remodeling and Control of Homologous Recombination by DNA Helicases and Translocases that Target Recombinases and SynapsisManipulation of DNA Repair Proficiency in Mouse Models of Colorectal CancerG-quadruplexes and helicasesMechanisms of Origin, Phenotypic Effects and Diagnostic Implications of Complex Chromosome RearrangementsInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapyThe role of RecQ helicases in non-homologous end-joiningRoles of DNA helicases in the maintenance of genome integrityThe SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans MeiosisPlasmodium falciparum Werner homologue is a nuclear protein and its biochemical activities reside in the N-terminal regionControlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMOPhysiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear Edgep53 in the DNA-Damage-Repair ProcessDifferential Protein Distribution between the Nucleus and Mitochondria: Implications in AgingSystemic DNA damage responses in aging and diseasesNuclear DNA damage signalling to mitochondria in ageingThe DNA structure and sequence preferences of WRN underlie its function in telomeric recombination eventsETAA1 acts at stalled replication forks to maintain genome integrityHow Research on Human Progeroid and Antigeroid Syndromes Can Contribute to the Longevity Dividend InitiativeBLM helicase facilitates telomere replication during leading strand synthesis of telomeresWRN regulates pathway choice between classical and alternative non-homologous end joiningA helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.Drugging the Cancers Addicted to DNA Repair.Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.The role of post-translational modifications in fine-tuning BLM helicase function during DNA repairCatalytic activities of Werner protein are affected by adduction with 4-hydroxy-2-nonenalThe intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structuresMolecular characterization of an intact p53 pathway subtype in high-grade serous ovarian cancer.RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers.Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases.RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling.Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.BLM unfolds G-quadruplexes in different structural environments through different mechanismsProtein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stabilitySLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediatesThe Extraintestinal Pathogenic Escherichia coli Factor RqlI Constrains the Genotoxic Effects of the RecQ-Like Helicase RqlH.RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins."...Rewritten in the skin": clues to skin biology and aging from inherited disease.
P2860
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P2860
Human RecQ helicases in DNA repair, recombination, and replication.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Human RecQ helicases in DNA repair, recombination, and replication.
@ast
Human RecQ helicases in DNA repair, recombination, and replication.
@en
type
label
Human RecQ helicases in DNA repair, recombination, and replication.
@ast
Human RecQ helicases in DNA repair, recombination, and replication.
@en
prefLabel
Human RecQ helicases in DNA repair, recombination, and replication.
@ast
Human RecQ helicases in DNA repair, recombination, and replication.
@en
P2093
P2860
P1476
Human RecQ helicases in DNA repair, recombination, and replication
@en
P2093
Deborah L Croteau
Venkateswarlu Popuri
Vilhelm A Bohr
P2860
P304
P356
10.1146/ANNUREV-BIOCHEM-060713-035428
P577
2014-03-03T00:00:00Z