A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
about
Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophagesDYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 bindingThe WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functionsPKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific mannersProtein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligaseATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damageRegulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylationThe kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel diseaseDual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusionGenomic screening with RNAi: results and challengesDown's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1Epigenetic principles and mechanisms underlying nervous system functions in health and diseaseDYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeCounteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein PhosphatasesNuclear factor of activated T cells - a transcription factor family as critical regulator in lung and colon cancerCalcineurin-Crz1 signaling in lower eukaryotesNFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer ProteinsStructures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate RecognitionMetabolic syndrome: genetic insights into disease pathogenesisTMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signalingPPARalpha siRNA-treated expression profiles uncover the causal sufficiency network for compound-induced liver hypertrophyDephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complexDYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeepingHerpesviral G protein-coupled receptors activate NFAT to induce tumor formation via inhibiting the SERCA calcium ATPaseIntegration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1ASelective inhibition of the kinase DYRK1A by targeting its folding processOsteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis.Factors affecting reproducibility between genome-scale siRNA-based screens.Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc.dDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in DrosophilaA network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila.SIFamide and SIFamide receptor defines a novel neuropeptide signaling to promote sleep in Drosophila.Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatinMolecular basis of calcium signaling in lymphocytes: STIM and ORAINFAT proteins: emerging roles in cancer progression.Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis.A primer on using pooled shRNA libraries for functional genomic screensDyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
P2860
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P2860
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
description
2006 nî lūn-bûn
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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@ast
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@en
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@en-gb
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@nl
type
label
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@ast
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@en
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@en-gb
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@nl
prefLabel
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@ast
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@en
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@en-gb
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@nl
P2093
P921
P3181
P356
P1433
P1476
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
@en
P2093
Alina Iuga
Anjana Rao
Bogdan Tanasa
Diana Bolton
Heidi Okamura
Julie Nardone
Patrick G Hogan
Sonal Srikanth
Sonia Sharma
Stefan Feske
P2888
P304
P3181
P356
10.1038/NATURE04631
P407
P577
2006-06-01T00:00:00Z
P5875
P6179
1003307032