Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromer
about
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIαVARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surfaceRME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation.Role of the Retromer Complex in Neurodegenerative DiseasesCapping protein regulators fine-tune actin assembly dynamicsFunction and regulation of the endosomal fusion and fission machineriesRetromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in DrosophilaRetromer-mediated endosomal protein sorting: all WASHed up!CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDLMutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagyWash functions downstream of Rho1 GTPase in a subset of Drosophila immune cell developmental migrations.A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.Retromer: a master conductor of endosome sorting.Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells.Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling.VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras traffickingWASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptorsGenetics and genomics of Parkinson's disease.Retromer-mediated endosomal protein sorting: The role of unstructured domains.Systems-wide Studies Uncover Commander, a Multiprotein Complex Essential to Human Development.Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutationUpdated Insight into the Physiological and Pathological Roles of the Retromer Complex.Mroh1, a lysosomal regulator localized by WASH-generated actin.Analysis of the Retromer complex-WASH complex interaction illuminates new avenues to explore in Parkinson disease.The Arp2/3 Regulatory System and Its Deregulation in Cancer.Retromer and the cation-independent mannose 6-phosphate receptor-Time for a trial separation?Actin assembly mediated by a nucleation promoting factor WASH is involved in MTOC-TMA formation during Xenopus oocyte maturation.De novo deleterious genetic variations target a biological network centered on Aβ peptide in early-onset Alzheimer disease.HRS-WASH axis governs actin-mediated endosomal recycling and cell invasion.
P2860
Q24292907-B65D4DD1-3AF7-4CDE-905E-5A2459A3DB4EQ24298162-1808B7DF-A917-4C33-8101-1E05563C451FQ24339406-9A90C436-A571-4915-85C5-6F0F5A50D31CQ26766012-768A8FF2-CD92-450A-B7A4-336C2FD9FFABQ27006034-4E2DC7FB-A385-422F-A97E-D51B44D6FAC4Q27015677-7E4609CC-70FE-48BD-94DC-C8695C6C2F07Q28115507-D91225EA-8035-4698-91AF-7BD9BF5E2435Q28291654-3F074CDE-5FF5-4892-BA90-2CF0E1254872Q28975614-D3352CE3-1903-4CFF-8A75-20CA12316020Q30578370-D1B6ED88-DFD7-4F95-A05A-490A8082C356Q30651019-24F2E895-03B9-4F8C-BD98-C0BF6FEB0073Q34144487-44091BB9-E6D2-4400-A557-F207D00716E0Q34401990-67477C87-DEF8-438C-813D-F364ABEB5F69Q34961689-FC467EAE-27CE-4DD0-B6F4-7556E5217FAAQ36987597-0D7A73D3-637E-4C88-9D9B-F8476EDE50E4Q37180578-B8ED0DF9-BAC0-44C2-8167-DDA3EB47C858Q37323063-44B1E809-5A26-4BCF-A8FA-E3CEFC7371E5Q38233866-2DBB2021-3847-415F-BFFF-DCF34A2609F7Q38527246-BF85BC1C-DEFC-42A1-8517-478C94630583Q38678916-CD73BD1D-5D64-4F76-A5D3-D187D592AF1CQ38979528-0422A8E5-B3B4-493A-B329-47672DD3FFEDQ41572903-8ACE69B0-A12D-4784-8343-717872B0FF70Q42236307-17EAD248-E432-48F7-8B10-C79380BB1394Q42742451-B3F46461-1E84-40D0-ADBB-2AEBF5DDDA1EQ47322418-4B42E850-20DF-4763-AEDF-D401F3C50F73Q47601633-E2F4424B-7C67-4A38-BC56-2D2CD7F7FD4FQ48505324-022575DD-EA80-4E0B-949D-708D796ECB63Q50953138-AC347548-D315-42F8-87EF-399D6908583EQ54976499-C7A1DCBD-6F41-410D-B275-2C3C75466DE9
P2860
Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromer
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Endosomal recruitment of the W ...... interaction with the retromer
@ast
Endosomal recruitment of the W ...... interaction with the retromer
@en
Endosomal recruitment of the W ...... interaction with the retromer
@en-gb
Endosomal recruitment of the W ...... interaction with the retromer
@nl
type
label
Endosomal recruitment of the W ...... interaction with the retromer
@ast
Endosomal recruitment of the W ...... interaction with the retromer
@en
Endosomal recruitment of the W ...... interaction with the retromer
@en-gb
Endosomal recruitment of the W ...... interaction with the retromer
@nl
prefLabel
Endosomal recruitment of the W ...... interaction with the retromer
@ast
Endosomal recruitment of the W ...... interaction with the retromer
@en
Endosomal recruitment of the W ...... interaction with the retromer
@en-gb
Endosomal recruitment of the W ...... interaction with the retromer
@nl
P2093
P2860
P921
P356
P1433
P1476
Endosomal recruitment of the W ...... interaction with the retromer
@en
P2093
Carla Sousa-Blin
Goran Lakisic
Larisa Volceanov
Matthew N J Seaman
Michael E Harbour
Véronique Henriot
P2860
P304
P356
10.1111/BOC.201200038
P407
P577
2013-05-01T00:00:00Z