DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange
about
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage responseNUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stabilityRad5 template switch pathway of DNA damage tolerance determines synergism between cisplatin and NSC109268 in Saccharomyces cerevisiaePARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress.DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.Replication protein A: single-stranded DNA's first responder: dynamic DNA-interactions allow replication protein A to direct single-strand DNA intermediates into different pathways for synthesis or repair.Rfa2 is specifically dephosphorylated by Pph3 in Candida albicans.A whole-genome RNA interference screen for human cell factors affecting myxoma virus replicationTwo distinct modes of ATR activation orchestrated by Rad17 and Nbs1.Zinc finger protein 668 interacts with Tip60 to promote H2AX acetylation after DNA damageDNA structure-specific priming of ATR activation by DNA-PKcsPhosphorylation and cellular function of the human Rpa2 N-terminus in the budding yeast Saccharomyces cerevisiae.HARP preferentially co-purifies with RPA bound to DNA-PK and blocks RPA phosphorylationThe DNA damage response and checkpoint adaptation in Saccharomyces cerevisiae: distinct roles for the replication protein A2 (Rfa2) N-terminus.DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network.Controlling DNA-end resection: a new task for CDKs.Chemotherapy induced DNA damage response: convergence of drugs and pathwaysDNA-dependent protein kinase and DNA repair: relevance to Alzheimer's disease.Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells.A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination.PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway.SLFN11 Blocks Stressed Replication Forks Independently of ATR.deletion in luminal cells of mature prostate induces replication stress and senescence in vivo
P2860
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P2860
DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@ast
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@en
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@en-gb
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@nl
type
label
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@ast
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@en
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@en-gb
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@nl
prefLabel
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@ast
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@en
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@en-gb
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@nl
P2860
P921
P1433
P1476
DNA-PK-dependent RPA2 hyperpho ...... sses sister chromatid exchange
@en
P2093
Deokjae Lee
Kyungjae Myung
P2860
P304
P356
10.1371/JOURNAL.PONE.0021424
P407
P577
2011-01-01T00:00:00Z