Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity - Test2 - elhamkhani - TriplyDB

Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity

Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity

http://www.wikidata.org/entity/Q24315264

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NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4 The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation Molecular basis for N-terminal acetylation by the heterodimeric NatA complex Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases.Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo.Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects Drosophila variable nurse cells encodes arrest defective 1 (ARD1), the catalytic subunit of the major N-terminal acetyltransferase complex A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation The molecular basis for histone H4- and H2A-specific amino-terminal acetylation by NatD Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase The biological functions of Naa10 - From amino-terminal acetylation to human disease Quantitative proteomic analysis of histone modifications Human Naa50 Protein Displays Broad Substrate Specificity for Amino-terminal Acetylation: DETAILED STRUCTURAL AND BIOCHEMICAL ANALYSIS USING TETRAPEPTIDE LIBRARY.Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion.N-terminal acetylation inhibits protein targeting to the endoplasmic reticulum Protein N-terminal acetyltransferases in cancer.Chemoproteomic profiling of lysine acetyltransferases highlights an expanded landscape of catalytic acetylation Specificity and versatility of substrate binding sites in four catalytic domains of human N-terminal acetyltransferases.A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation.Fine-mapping and genetic analysis of the loci affecting hepatic iron overload in mice.Molecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling.Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications.Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms.Targeted large-scale analysis of protein acetylation.Protein alpha-N-acetylation studied by N-terminomics.Developmental roles of protein N-terminal acetylation.Chemical Biology for Investigating Epigenetic Functions of Lysine Acetyltransferases (KATs).A Role for Human N-alpha Acetyltransferase 30 (Naa30) in Maintaining Mitochondrial Integrity.High expression of Naa10p associates with lymph node metastasis and predicts favorable prognosis of oral squamous cell carcinoma.Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis.Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion.Microscopy-based Saccharomyces cerevisiae complementation model reveals functional conservation and redundancy of N-terminal acetyltransferases.Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study.

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P2860

Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity

http://www.wikidata.org/entity/Q24315264

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@ast

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@en

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@en-gb

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@nl

type

label

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@ast

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@en

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@en-gb

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

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prefLabel

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@ast

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@en

Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

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Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

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JBC.M109.001347

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Journal of Biological Chemistry

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Human Naa50p (Nat5/San) displa ...... lon-acetyltransferase activity

@en

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Johan R Lillehaug

http://www.w3.org/2001/XMLSchema#string

Odd A Karlsen

http://www.w3.org/2001/XMLSchema#string

P2860

The acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent manner

Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex

Interaction between the human nuclear cap-binding protein complex and hnRNP F

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides

Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity.

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31122-9

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scholarly article

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3918133

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10.1074/JBC.M109.001347

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45

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284

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Mathias Ziegler

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2009-11-06T00:00:00Z

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19744929

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peptidyl-lysine acetyltransferase activity

N-alpha-acetyltransferase 50, NatE catalytic subunit

P932

2781511

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