Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization - Test2 - elhamkhani - TriplyDB

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

http://www.wikidata.org/entity/Q24319663

about

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation Composition and biological significance of the human Nα-terminal acetyltransferases A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1)The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4 Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects The DAF-16 FOXO transcription factor regulates natc-1 to modulate stress resistance in Caenorhabditis elegans, linking insulin/IGF-1 signaling to protein N-terminal acetylation Molecular basis for N-terminal acetylation by the heterodimeric NatA complex N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases.N-terminal acetylation by NatC is not a general determinant for substrate subcellular localization in Saccharomyces cerevisiae Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo.Arf-like GTPase Arl8: Moving from the periphery to the center of lysosomal biology Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase New links between protein N-terminal acetylation, dauer diapause, and the insulin/IGF-1 signaling pathway in Caenorhabditis elegans Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation The biological functions of Naa10 - From amino-terminal acetylation to human disease Influence of the sequence environment and properties of neighboring amino acids on amino-acetylation: relevance for structure-function analysis.Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion.Protein N-terminal acetylation: NAT 2007-2008 Symposia.A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates Application of reverse-phase HPLC to quantify oligopeptide acetylation eliminates interference from unspecific acetyl CoA hydrolysis.Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome Viruses and prions of Saccharomyces cerevisiae The N-end rule pathway and regulation by proteolysis Protein N-terminal acetyltransferases in cancer.Specificity and versatility of substrate binding sites in four catalytic domains of human N-terminal acetyltransferases.Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein.Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms.Protein acetylation in archaea, bacteria, and eukaryotes Targeted large-scale analysis of protein acetylation.Protein alpha-N-acetylation studied by N-terminomics.Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway Developmental roles of protein N-terminal acetylation.Vitrification at the pre-antral stage transiently alters inner mitochondrial membrane potential but proteome of in vitro grown and matured mouse oocytes appears unaffected.A Role for Human N-alpha Acetyltransferase 30 (Naa30) in Maintaining Mitochondrial Integrity.

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P2860

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

http://www.wikidata.org/entity/Q24319663

description

2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Molecular and Cellular Biology

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Knockdown of human N alpha-ter ...... rrant human Arl8b localization

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Anita Ryningen

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Darina Gromyko

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Johan R Lillehaug

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Kristian K Starheim

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P2860

NATH, a novel gene overexpressed in papillary thyroid carcinomas

Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex

Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase

The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

The Jalview Java alignment editor

N-terminal acetyltransferases and sequence requirements for N-terminal acetylation of eukaryotic proteins.

The molecular chaperone Ssb from Saccharomyces cerevisiae is a component of the ribosome-nascent chain complex.

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3569-81

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scholarly article

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3918136

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10.1128/MCB.01909-08

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13

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29

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Jan Erik Varhaug

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2009-07-01T00:00:00Z

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P698

19398576

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apoptotic process

N-alpha-acetyltransferase 38, NatC auxiliary subunit

N-alpha-acetyltransferase 30, NatC catalytic subunit

N-alpha-acetyltransferase 35, NatC auxiliary subunit

P932

2698767

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