Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
about
N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effectsImplications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal orthologThree-dimensional structure of aStreptomyces sviceusGNAT acetyltransferase with similarity to the C-terminal domain of the human GH84O-GlcNAcaseStructural basis for substrate-specific acetylation of Nα-acetyltransferase Ard1 from Sulfolobus solfataricusMultiple Conformations of the Loop Region Confers Heat-Resistance on SsArd1, a Thermophilic NatADe novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and femalesNuclear translocation of hARD1 contributes to proper cell cycle progressionNAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defectsA Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutantA direct, ratiometric, and quantitative MALDI-MS assay for protein methyltransferases and acetyltransferasesCrystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific AcetylationThe molecular basis for histone H4- and H2A-specific amino-terminal acetylation by NatDStructure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferaseThe biological functions of Naa10 - From amino-terminal acetylation to human diseaseMolecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1.Human Naa50 Protein Displays Broad Substrate Specificity for Amino-terminal Acetylation: DETAILED STRUCTURAL AND BIOCHEMICAL ANALYSIS USING TETRAPEPTIDE LIBRARY.Identification of the sequence determinants of protein N-terminal acetylation through a decision tree approach.Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in ArabidopsisTubedown regulation of retinal endothelial permeability signaling pathways.NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment.Acetyl group coordinated progression through the catalytic cycle of an arylalkylamine N-acetyltransferaseMolecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling.Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms.The N-terminal Acetyltransferase Naa10/ARD1 Does Not Acetylate Lysine Residues.N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi.Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation DeficiencyProteomic and genomic characterization of a yeast model for Ogden syndrome.Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.Protein N-terminal Acetylation by the NatA Complex Is Critical for Selective Mitochondrial Degradation.The N-terminal acetyltransferase Naa10 is essential for zebrafish development.Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion.The rate of cis-trans conformation errors is increasing in low-resolution crystal structures.Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases.Structural basis of HypK regulating N-terminal acetylation by the NatA complex.Characterization of histone acylations links chromatin modifications with metabolismProbing the interaction between NatA and the ribosome for co-translational protein acetylation.[14C]-Acetyl-Coenzyme A-Based In Vitro N-Terminal Acetylation Assay.Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report.
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P2860
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@ast
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@en
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@nl
type
label
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@ast
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@en
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@nl
prefLabel
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@ast
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@en
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
@en
P2093
E James Petersson
Glen Liszczak
Jacob M Goldberg
P2860
P2888
P304
P3181
P356
10.1038/NSMB.2636
P407
P577
2013-09-01T00:00:00Z
P5875
P6179
1051661708