Road to ruin: targeting proteins for degradation in the endoplasmic reticulum - Test2 - elhamkhani - TriplyDB

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

http://www.wikidata.org/entity/Q26866096

about

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation Mpl traffics to the cell surface through conventional and unconventional routes EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation NMR characterization of the interaction between the PUB domain of peptide:N-glycanase and ubiquitin-like domain of HR23 USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates Role of ROS and RNS Sources in Physiological and Pathological Conditions Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets Protein Folding and Mechanisms of Proteostasis Endoplasmic reticulum-mediated protein quality control in Arabidopsis Emerging functions of the unfolded protein response in immunity Can too many copies spoil the broth?How viruses use the endoplasmic reticulum for entry, replication, and assembly Xenobiotic perturbation of ER stress and the unfolded protein response Mechanisms of protein-folding diseases at a glance mTORC1 signaling activates NRF1 to increase cellular proteasome levels INS-gene mutations: from genetics and beta cell biology to clinical disease Conversion of psychological stress into cellular stress response: roles of the sigma-1 receptor in the process Protein degradation pathways in Parkinson's disease: curse or blessing The Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer Therapeutics Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway.Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria.Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome.An apicoplast localized ubiquitylation system is required for the import of nuclear-encoded plastid proteins Characterization of the ubiquitylating components of the human malaria parasite's protein degradation pathway Five Questions (with their Answers) on ER-Associated Degradation Endoplasmic reticulum quality control and systemic amyloid disease: Impacting protein stability from the inside out Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L Organizing principles of mammalian nonsense-mediated mRNA decay FBG1 Is the Final Arbitrator of A1AT-Z Degradation The critical role of membralin in postnatal motor neuron survival and disease BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism Evidence for glycoprotein transport into complex plastids

P2860

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P2860

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

http://www.wikidata.org/entity/Q26866096

description

2011 nî lūn-bûn

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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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type

label

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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prefLabel

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

@ast

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

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H. L. Ploegh

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J. S. Weissman

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M. H. Smith

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P2860

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

A membrane protein required for dislocation of misfolded proteins from the ER

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling

SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates

A luminal flavoprotein in endoplasmic reticulum-associated degradation

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

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22116878

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endoplasmic reticulum

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