Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling - Test2 - elhamkhani - TriplyDB

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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The dynamic cilium in human diseases A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSome BBS mutations modify phenotypic expression of CEP290-related ciliopathies The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia The blind leading the obese: the molecular pathophysiology of a human obesity syndrome Childhood obesity The role of primary cilia in neuronal function Recent advances in understanding leptin signaling and leptin resistance Bardet-Biedl Syndrome 60 YEARS OF POMC: From POMC and α-MSH to PAM, molecular oxygen, copper, and vitamin C Leptin signaling and leptin resistance Primary cilia in the developing and mature brain Update on the genetics of bardet-biedl syndrome Ectopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null mice Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans GLUT4 defects in adipose tissue are early signs of metabolic alterations in Alms1GT/GT, a mouse model for obesity and insulin resistance Mouse models of ciliopathies: the state of the art.Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?Bardet-Biedl syndrome: Genetics, molecular pathophysiology, and disease management Magel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in mice Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice Gene therapy prevents photoreceptor death and preserves retinal function in a Bardet-Biedl syndrome mouse model.Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes.The primary cilium as a complex signaling center The cellular and molecular bases of leptin and ghrelin resistance in obesity.Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation Molecular signatures reveal circadian clocks may orchestrate the homeorhetic response to lactation Role of primary cilia in brain development and cancer New structural and functional contexts of the Dx[DN]xDG linear motif: insights into evolution of calcium-binding proteins Circannual transitions in gene expression: lessons from seasonal adaptations.Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice.Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of C. elegans Bardet-Biedl syndrome mutants.Hippocampal and cortical primary cilia are required for aversive memory in mice.Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia Cilia in the CNS: the quiet organelle claims center stage

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P2860

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

http://www.wikidata.org/entity/Q24317488

description

2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Human Molecular Genetics

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Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

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Deng-Fu Guo

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Donald A Morgan

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Kevin Bugge

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P2860

Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

Clinical and genetic epidemiology of Bardet-Biedl syndrome in Newfoundland: a 22-year prospective, population-based, cohort study

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin.

Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia

Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome

Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome

A knockin mouse model of the Bardet-Biedl syndrome 1 M390R mutation has cilia defects, ventriculomegaly, retinopathy, and obesity

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10.1093/HMG/DDP031

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7

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Val C Sheffield

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Golgi to plasma membrane protein transport

negative regulation of appetite by leptin-mediated signaling pathway

Bardet-Biedl syndrome 1

Bardet-Biedl syndrome 2

Bardet-Biedl syndrome 4 (human)

Bardet-Biedl syndrome 2 (human)

Leptin receptor

McKusick-Kaufman syndrome

Bardet-Biedl syndrome 1 (human)

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