Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation
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Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctionsNectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing proteinMSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemiaThe t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein familyLeucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemiaThe carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ proteinInteractions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteinst(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromesCingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosinThe junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilinPDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptorAfadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junctionThe Ras target AF-6 is a substrate of the fam deubiquitinating enzymeThe Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domainMolecular genetic dissection of mouse unconventional myosin-VA: tail region mutationsTwo cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteinsNectin: an adhesion molecule involved in formation of synapsesCopy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants.The PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled.Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6.Involvement of the ALL-1 gene in a solid tumor.Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains.Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrainAfadin regulates puncta adherentia junction formation and presynaptic differentiation in hippocampal neurons.Genetic ablation of afadin causes mislocalization and deformation of Paneth cells in the mouse small intestinal epithelium.ALL-1 partial duplication in acute leukemia.Loss of the tight junction MAGUK ZO-1 in breast cancer: relationship to glandular differentiation and loss of heterozygosity.Developmental analysis and subcellular localization of the murine homologue of ELL.The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells.Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis.Cell polarity proteins: common targets for tumorigenic human viruses.Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.PHF10 is required for cell proliferation in normal and SV40-immortalized human fibroblast cellsCloning and characterization of myr 6, an unconventional myosin of the dilute/myosin-V family.The adherens junction protein afadin is an AKT substrate that regulates breast cancer cell migration.Functional analysis of the leukemia protein ELL: evidence for a role in the regulation of cell growth and survival.alpha-catenin-independent recruitment of ZO-1 to nectin-based cell-cell adhesion sites through afadin.Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.Identification of MLL partner genes in 27 patients with acute leukemia from a single cytogenetic laboratory.
P2860
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P2860
Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation
description
1993 nî lūn-bûn
@nan
1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@ast
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@en
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@en-gb
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@nl
type
label
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@ast
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@en
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@en-gb
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@nl
prefLabel
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@ast
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@en
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@en-gb
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@nl
P2093
P921
P1433
P1476
Cloning of the ALL-1 fusion pa ...... 6;11) chromosome translocation
@en
P2093
K Kuriyama
P C Nowell
T Nakamura
P304
P407
P577
1993-12-01T00:00:00Z