SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
about
Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingAdvances in Autophagy Regulatory MechanismsNutrient sensing, metabolism, and cell growth controlRegulation of mTORC1 by amino acidsNutrient regulation of the mTOR complex 1 signaling pathwayReciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy.A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylationThe proline-rich region of glyceraldehyde-3-phosphate dehydrogenase from human sperm may bind SH3 domains, as revealed by a bioinformatic study of low-complexity protein segments.dRAGging amino acid-mTORC1 signaling by SH3BP4.Amino acid signalling upstream of mTORNutrient signaling to mTOR and cell growth.Growing knowledge of the mTOR signaling network.An ancient autoproteolytic domain found in GAIN, ZU5 and Nucleoporin98SEA you later alli-GATOR--a dynamic regulator of the TORC1 stress response pathway.Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPasesThe lysosome as a command-and-control center for cellular metabolism.The pretransplant systemic metabolic profile reflects a risk of acute graft versus host disease after allogeneic stem cell transplantation.Control of cell growth: Rag GTPases in activation of TORC1.Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.Getting ready for building: signaling and autophagosome biogenesis.Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids.Macrophage defense mechanisms against intracellular bacteria.The Systemic Control of Growth.Rag GTPase in amino acid signaling.The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.SH3BP4, a novel pigmentation gene, is inversely regulated by miR-125b and MITF.The Architecture of the Rag GTPase Signaling Network.Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation.Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.Rags to riches: Amino acid sensing by the Rag GTPases in health and disease.mTORC1 as the main gateway to autophagy.A polynomial based model for cell fate prediction in human diseases.The Early Dendritic Cell Signaling Induced by Virulent Francisella tularensis Strain Occurs in Phases and Involves the Activation of Extracellular Signal-Regulated Kinases (ERKs) and p38 In the Later Stage.Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action.mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome.
P2860
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P2860
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@ast
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@en
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@en-gb
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@nl
type
label
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@ast
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@en
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@en-gb
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@nl
prefLabel
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@ast
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@en
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@en-gb
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@nl
P2093
P2860
P921
P3181
P1433
P1476
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling
@en
P2093
Jane R Dunlevy
Matthew Stone
Tae Hyun Hwang
Timothy J Griffin
Yeon-Gil Kim
Young-Mi Kim
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2012.04.007
P407
P50
P577
2012-06-29T00:00:00Z