Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
about
Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressorHuman PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiationA supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damageMolecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIFPHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53Functional Evolution of BRCT Domains from Binding DNA to ProteinBRCT domains: easy as one, two, threeComparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysisStructural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damageSolution Structure of Polymerase μ's BRCT Domain Reveals an Element Essential for Its Role in Nonhomologous End Joining †Structure and Dynamics of the P7 Protein from the Bacteriophage ϕ12Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repairA Pocket on the Surface of the N-Terminal BRCT Domain of Mcph1 Is Required to Prevent Abnormal Chromosome CondensationStructure of the DNA-bound BRCA1 C-terminal Region from Human Replication Factor C p140 and Model of the Protein-DNA ComplexThe structural basis for partitioning of the XRCC1/DNA ligase III- BRCT-mediated dimer complexesStructure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage RepairNibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylationNFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage responseStructure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancerThe 8-kDa dynein light chain binds to p53-binding protein 1 and mediates DNA damage-induced p53 nuclear accumulationp53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening systemBRCT domains: A little more than kin, and less than kindDNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions.Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs.Stability of the core domain of p53: insights from computer simulations.USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism.{Delta}Np73{beta} puts the brakes on DNA repair.Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathwayDetermination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in miceComputational Identification of MoRFs in Protein Sequences Using Hierarchical Application of Bayes Rulep53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in miceTandem BRCT Domains: DNA's Praetorian Guard.Tying the loose ends together in DNA double strand break repair with 53BP1.Structural basis for understanding oncogenic p53 mutations and designing rescue drugs.Effects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia.Low-dose ionizing irradiation triggers a 53BP1 response to DNA double strand breaks in mouse spermatogonial stem cells.Surf the post-translational modification network of p53 regulationGenetic polymorphisms and cervical cancer development: ATM G5557A and p53bp1 C1236G.
P2860
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P2860
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor
@nl
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
@ast
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
@en
type
label
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor
@nl
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
@ast
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
@en
prefLabel
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor
@nl
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
@ast
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
@en
P2093
P2860
P3181
P356
P1433
P1476
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
@en
P2093
Aidan J Doherty
Balaku P Basu
Dean J Derbyshire
Kuniyoshi Iwabuchi
Takayasu Date
P2860
P304
P3181
P356
10.1093/EMBOJ/CDF383
P407
P577
2002-07-01T00:00:00Z