BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
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Mitochondria, cholesterol and cancer cell metabolismThe ubiquitin system: a critical regulator of innate immunity and pathogen-host interactionsInactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasisHow to unleash mitochondrial apoptotic blockades to kill cancers?Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway.BOK displays cell death-independent tumor suppressor activity in non-small-cell lung carcinoma.Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis.Non-apoptotic functions of BCL-2 family proteins.To Prime, or Not to Prime: That Is the Question.Physiological and Pharmacological Control of BAK, BAX, and Beyond.Bax and Bak Pores: Are We Closing the Circle?TMBIM-mediated Ca2+ homeostasis and cell death.BCL-2 family: integrating stress responses at the ER to control cell demise.Targeting VCP enhances anticancer activity of oncolytic virus M1 in hepatocellular carcinoma.The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection.miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development.Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimeticsExtra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.MOMP, cell suicide as a BCL-2 family business.Why do BCL-2 inhibitors work and where should we use them in the clinic?Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die.BOK promotes chemical-induced hepatocarcinogenesis in mice.Bax, Bak and beyond - mitochondrial performance in apoptosis.Viewing BCL2 and cell death control from an evolutionary perspective.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID.Ceramide-induced BOK promotes mitochondrial fission in preeclampsia.How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?There is something about BOK we just don't get yet.CDK5-Mediated Phosphorylation-Dependent Ubiquitination and Degradation of E3 Ubiquitin Ligases GP78 Accelerates Neuronal Death in Parkinson's Disease.Targeting BCL-2 regulated apoptosis in cancer.Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL.Characterization of MLKL-mediated Plasma Membrane Rupture in NecroptosisContribution of BH3-domain and Transmembrane-domain to the Activity and Interaction of the Pore-forming Bcl-2 Proteins Bok, Bak, and Bax
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BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
description
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2016
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im April 2016 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2016/04/07)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/04/07)
@nl
наукова стаття, опублікована у квітні 2016
@uk
مقالة علمية (نشرت في 7-4-2016)
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name
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
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BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@en
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@nl
type
label
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@ast
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@en
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@nl
prefLabel
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@ast
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@en
BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@nl
P2093
P2860
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BOK Is a Non-canonical BCL-2 F ...... d by ER-Associated Degradation
@en
P2093
Bernadette Victor
Desiree M Schneider
Fabien Llambi
Melissa J Parsons
Scott A Brown
Sébastien Gingras
Taosheng Chen
Yue-Ming Wang
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P304
P3181
P356
10.1016/J.CELL.2016.02.026
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P577
2016-03-03T00:00:00Z