Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
about
SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processingIs NF-kappaB a good target for cancer therapy? Hopes and pitfallsRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsSelf-termination of the terminatorThe RET/PTC3 oncogene activates classical NF-κB by stabilizing NIKEndothelial cell dysfunction in viral hemorrhage and edema.Signaling to NF-kappaB: regulation by ubiquitination.CD40 is essential in the upregulation of TRAF proteins and NF-kappaB-dependent proinflammatory gene expression after arterial injuryThe adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.Emerging complexity of protein ubiquitination in the NF-κB pathway.Nuclear factor-κB-inducing kinase (NIK) contains an amino-terminal inhibitor of apoptosis (IAP)-binding motif (IBM) that potentiates NIK degradation by cellular IAP1 (c-IAP1).The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitinationExome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutationsLipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.Hantavirus regulation of type I interferon responses.Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signallingNIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells.The NY-1 hantavirus Gn cytoplasmic tail coprecipitates TRAF3 and inhibits cellular interferon responses by disrupting TBK1-TRAF3 complex formation.IL-17 induces expression of vascular cell adhesion molecule through signalling pathway of NF-κB, but not Akt1 and TAK1 in vascular smooth muscle cells.Smac mimetics and TNFalpha: a dangerous liaison?Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancerNF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism.The interleukin-1 receptor-associated kinase M selectively inhibits the alternative, instead of the classical NFkappaB pathway.Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation.Nod-like receptors in intestinal homeostasis, inflammation, and cancer.Non-canonical NF-κB signaling activation and regulation: principles and perspectives.Impairment of Mature B Cell Maintenance upon Combined Deletion of the Alternative NF-κB Transcription Factors RELB and NF-κB2 in B Cells.Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor.Activation-induced tumor necrosis factor receptor-associated factor 3 (Traf3) alternative splicing controls the noncanonical nuclear factor κB pathway and chemokine expression in human T cells.A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes.Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLDThe RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB.Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.The Toll-like receptor 1/2 agonists Pam(3) CSK(4) and human β-defensin-3 differentially induce interleukin-10 and nuclear factor-κB signalling patterns in human monocytes.Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33).
P2860
Q24312155-A8CE5734-CAF0-4992-B484-9296B6835CCBQ24570128-67734F77-DEFD-4724-B15D-95D942DF1373Q26853280-896890BA-BB45-4579-BAA1-D625D91D5031Q28118772-0E960EFA-98C6-4264-B54C-58CC5B531C4CQ28511823-BCEB2675-0C5D-455B-9474-4FAED2EB249AQ33419868-DE52F178-CE6D-4714-906F-0454A36F2AB7Q33693806-5C919A9A-199F-417D-9A33-3D77400A8C9EQ34005419-2D5CB7C8-0399-465F-9A63-4313D1DE0D12Q34071164-80D0CE61-D8DA-4650-A8C5-18ECFADE4512Q34340648-F294D747-5C70-4859-9426-026037398EB9Q34346080-43079C29-7220-431D-91BD-FC163FB64516Q34431075-8F709E33-8100-4B98-B6AF-FF15541AC351Q34490165-8E304111-2456-4A28-916B-2849B43A4272Q34549536-6A08A16C-8494-4BE3-AB0A-7C86C5851632Q34682122-B1C3EEB5-4BD7-4512-B64E-23BDBDE1398EQ35588767-EA080CD1-1A9E-4C18-BABC-5458EE34D611Q36155317-C2B384CC-A0DC-42E8-AAC2-C6449CE186A5Q36177564-A73141E3-F384-44D2-A8AC-4FF0E9780809Q36591276-A2F23808-11AE-4C85-AB08-9D49F4AC57CAQ36825184-188B84B8-7452-4469-BDDA-A82FF844B7ADQ36898687-021B589D-225E-428C-A666-A34D6A82C9F7Q36931795-AB49AB5C-7C1C-4C8F-8F66-E04DD4DA9012Q37005632-1AACE1AC-941F-4FE9-8BFF-65B4911B9E21Q37178911-B939CD0E-BC3D-4323-93EC-74D3EAE1B6FDQ37187527-CA64A0A4-A259-43A1-AE82-577B664405E6Q37363042-D94419E0-758D-42B5-9F25-1CE2DEE74276Q37374200-D029ACF0-EC23-48F0-AF65-7E6974F51C0FQ37410560-26DEC47C-DC69-428D-A4F6-E64F8440F333Q37886430-007CDB9D-FF3E-4C2B-AFB1-89D3E219774CQ37948121-81422F38-C3D2-42BC-91D0-13F8459C9879Q38798777-948CD02E-1CB4-4AC4-9971-DCAC2817AA43Q38960255-24937923-5826-41FF-A188-44EFBC690EB6Q39011442-74C5DB99-240A-48E6-855B-B556C055648DQ39037203-96A51671-D229-4CE8-A37F-A4E774543F94Q41782395-CDFB34B5-96E2-450E-BAA1-90FA84400F5EQ42148237-81B6F1BA-253D-45FB-B4DB-B0CA904BD630Q43142702-ACF10A6D-F385-49CF-A8FD-68D491A584D1Q44221211-366E925B-3D3A-429C-95DA-DCAF8BD8ED97Q55052168-449F59EA-6650-4C27-A666-F906E54A3836
P2860
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@ast
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@en
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@en-gb
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@nl
type
label
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@ast
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@en
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@en-gb
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@nl
prefLabel
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@ast
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@en
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@en-gb
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@nl
P2093
P356
P1476
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway
@en
P2093
Brian Zarnegar
Jason R Kang
Jeannie Q He
Supriya K Saha
P304
P356
10.1074/JBC.M610271200
P407
P577
2007-02-09T00:00:00Z