Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.
about
An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitinationTWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptorThe USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2OTUB1 modulates c-IAP1 stability to regulate signalling pathwaysHOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complexA NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1Is NF-kappaB a good target for cancer therapy? Hopes and pitfallsThe Ubiquitination of NF-κB Subunits in the Control of TranscriptionThe Regulation of NF-κB Subunits by PhosphorylationDED or alive: assembly and regulation of the death effector domain complexesNF-κB, the first quarter-century: remarkable progress and outstanding questionsInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationRole of T cell-nuclear factor κB in transplantationRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsThe two faces of receptor interacting protein kinase-1The role of ubiquitylation in immune defence and pathogen evasionIAPs: a central element in the NF-κB activating signaling pathwayRoles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degenerationRoles of TRAF3 in T cells: many surprisesNon-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple JuncturesCrystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and RegulationNF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic ImplicationsTumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategiesTargeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell LymphomaThe seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosisNLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signalingThe RET/PTC3 oncogene activates classical NF-κB by stabilizing NIKOTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3Transcriptional repression of Bim by a novel YY1-RelA complex is essential for the survival and growth of Multiple MyelomaCellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicityc-IAP1 and c-IAP2 redundancy differs between T and B cells.Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profileSignaling to NF-kappaB: regulation by ubiquitination.Non-canonical NF-κB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2.Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral responseA new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling.NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis.RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3Classical and/or alternative NF-kappaB pathway activation in multiple myeloma.
P2860
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P2860
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Nonredundant and complementary ...... ternative NF-kappaB signaling.
@en
Nonredundant and complementary ...... ternative NF-kappaB signaling.
@nl
type
label
Nonredundant and complementary ...... ternative NF-kappaB signaling.
@en
Nonredundant and complementary ...... ternative NF-kappaB signaling.
@nl
prefLabel
Nonredundant and complementary ...... ternative NF-kappaB signaling.
@en
Nonredundant and complementary ...... ternative NF-kappaB signaling.
@nl
P2093
P2860
P356
P1433
P1476
Nonredundant and complementary ...... ternative NF-kappaB signaling.
@en
P2093
Atsushi Matsuzawa
Dario A A Vignali
Haopeng Wang
Jonathan J Keats
P Leif Bergsagel
Ping-Hui Tseng
Sivakumar Vallabhapurapu
Weizhou Zhang
P2860
P2888
P304
P356
10.1038/NI.1678
P407
P577
2008-11-09T00:00:00Z
P5875
P6179
1017708694