Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. - Test2 - elhamkhani - TriplyDB

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.

http://www.wikidata.org/entity/Q43142702

about

An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8 TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2 OTUB1 modulates c-IAP1 stability to regulate signalling pathways HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1 Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls The Ubiquitination of NF-κB Subunits in the Control of Transcription The Regulation of NF-κB Subunits by Phosphorylation DED or alive: assembly and regulation of the death effector domain complexes NF-κB, the first quarter-century: remarkable progress and outstanding questions Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation Role of T cell-nuclear factor κB in transplantation Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions The two faces of receptor interacting protein kinase-1 The role of ubiquitylation in immune defence and pathogen evasion IAPs: a central element in the NF-κB activating signaling pathway Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration Roles of TRAF3 in T cells: many surprises Non-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple Junctures Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation NF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic Implications Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3 Transcriptional repression of Bim by a novel YY1-RelA complex is essential for the survival and growth of Multiple Myeloma Cellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity c-IAP1 and c-IAP2 redundancy differs between T and B cells.Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile Signaling to NF-kappaB: regulation by ubiquitination.Non-canonical NF-κB activation and abnormal B cell accumulation in mice expressing ubiquitin protein ligase-inactive c-IAP2.Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling.NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis.RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3 Classical and/or alternative NF-kappaB pathway activation in multiple myeloma.

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P2860

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.

http://www.wikidata.org/entity/Q43142702

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

Nonredundant and complementary ...... ternative NF-kappaB signaling.

@en

Nonredundant and complementary ...... ternative NF-kappaB signaling.

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type

label

Nonredundant and complementary ...... ternative NF-kappaB signaling.

@en

Nonredundant and complementary ...... ternative NF-kappaB signaling.

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prefLabel

Nonredundant and complementary ...... ternative NF-kappaB signaling.

@en

Nonredundant and complementary ...... ternative NF-kappaB signaling.

@nl

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Nature Immunology

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Nonredundant and complementary ...... ternative NF-kappaB signaling.

@en

P2093

Atsushi Matsuzawa

http://www.w3.org/2001/XMLSchema#string

Dario A A Vignali

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Haopeng Wang

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Jonathan J Keats

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P Leif Bergsagel

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Ping-Hui Tseng

http://www.w3.org/2001/XMLSchema#string

Sivakumar Vallabhapurapu

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Weizhou Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

NF-kappaB regulation in the immune system

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

Regulatory functions of ubiquitination in the immune system

P2888

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1364-1370

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10.1038/NI.1678

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12

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9

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23462307

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1017708694

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18997792

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protein ubiquitination

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2671996

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