Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
about
sameAs
L-leucine 153 replaced with L-arginineL-arginine 173 replaced with glycineL-aspartic acid 406 replaced with L-valineL-cysteine 417 replaced with L-arginineL-arginine 175 replaced with L-prolineIKBKG ser-321 ser-325 ser-326 ser-unknown phosphorylatedIKBKG ser-285 phosphorylatedIKBKG ser-277 ser-309 phosphorylated
P279
TLR associated IKBKG variantsIKBKG:p-S176;S180-CHUK:p-S177;S181-IKBKBCHUK:IKBKB:IKBKGp-S177;S181-IKKB:IKKA:NEMOIKKA:IKKB:NEMOActive IKK complexPAMP:NOD oligomer:K63-polyUb-RIP2:NEMOPAMP:NOD oligomer:RIP2:NEMOK63polyUb-TRAF2;K63polyUb-TRAF6;K63polyUb-RIPK1;K63polyUb-IKBKGTRAF2;TRAF6;IKBKG;RIPK1Defective IKBKB (IKK2) does not form a complex with IKBKA and IKBKGIKBKA; IKBKB and IKBKG form IKK complexRIP2 binds NEMOPIAS4 SUMOylates IKBKG with SUMO1
P527
P688
Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosisvCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgammaSASH1 is a scaffold molecule in endothelial TLR4 signalingSequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stressThe zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signalingThe CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgammaBiochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)The IkappaB kinase complex: master regulator of NF-kappaB signalingIKK-gamma is an essential regulatory subunit of the IkappaB kinase complexThe E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMOThe Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMOOptineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIPRab11 endosomes contribute to mitotic spindle organization and orientationThe TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytesStructure of a NEMO/IKK-associating domain reveals architecture of the interaction siteTRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 LigaseTfR1 interacts with the IKK complex and is involved in IKK-NF-κB signallingA protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
P921
Q50370362-3705B307-2644-4623-9EF1-50DD41C483C0Q50370363-C9BBEB9D-29EE-4EFC-BE81-038FDD4882B9Q50370364-5B98E503-2811-4802-B422-65F6B83CD052Q50370366-DFE8E8C1-2B20-41F4-B718-F37626970186Q50370367-04569197-1CCF-449E-9BE4-9BBB5832C5CAQ50372158-FEBA6D73-22B3-4BC3-BA05-3AB3BC5CE79DQ50372269-4D6419C5-C2C6-4FDB-A606-A183D04A8A93Q56837734-E928817B-6044-4289-AB3B-0D5B5B73D9AB
P279
Q50257064-8273FDB6-05D1-4AB5-8A88-623DA3DEA23BQ50257067-8727E09C-CEB6-44D6-9F26-AC6DC0287CE7Q50259852-0BDA70ED-6FA3-4266-9BAE-3CD216F2DFEFQ50259855-0DFE96D0-62B4-41F0-8D53-5D8F6FFEB298Q50260050-80C57C8E-6B14-4477-941D-60A006F16067Q50260052-6C494C82-A355-40FF-83F0-E5A2BBFA8275Q50260796-330C9472-762E-49FA-9746-00E214D1EF1DQ50261438-B76A582D-1EA6-488A-8A2F-6D0EFE389475Q50268867-7C430C1D-EC67-4FE6-93C3-B2F106145C3AQ50268869-555F31C6-9E04-476F-B681-F9C0361ADB9FQ50289679-90228509-9546-498C-A05D-B4DB3D82F87DQ50291696-291F474A-A39F-4D00-AC16-CBAFC1091820Q50291950-158A2AD6-0338-462E-B3E2-9BB9EE3DBE7AQ56860549-0283245C-5F8E-48D3-9AB0-67F1EA26BA78
P527
Q22008750-362BE7A2-F62A-45A4-AAC8-40B5914C8BE2Q24290608-4C4AE032-57B9-4E71-B4B1-FE721E3FFBDFQ24295323-CE23F91B-2A5D-4112-AE75-F29FB9AC9CA9Q24300945-473914D3-EABE-41B1-A752-5A6BE0AA99A8Q24301538-81815093-1EB2-44C4-86AA-A549809A5E7CQ24302243-EC521772-986C-4BD0-B42D-47B5074C35F6Q24307730-72DCF023-5B48-43CB-9201-58B58D4EB03CQ24313366-836B3782-D676-4714-B17F-62B251A8B03DQ24316469-2288A878-E71C-4E1C-9CA9-186DFDCE7C34Q24321825-9A9F1C37-5DE8-43B7-A40E-84135BD3CBCFQ24336822-CA0CC614-0A19-45D1-A018-38CFD70D49B0Q24337587-EF7EAFD1-90C1-4B43-A632-1FE063BF8FBCQ24338107-54704790-D0E5-4D48-975A-8B0412BA0773Q24338639-A132E84B-0F80-4265-AD2E-438AB42E1D14Q27650555-01EA6EE2-D6C8-49E3-82C6-D7A9FF1590E4Q28118631-5EFB57CC-1FAA-4336-B7F7-ADE305BDD584Q36509188-63451C7F-895B-4694-89B1-F05046E4B71DQ60044295-B65DC93B-B3EB-42D0-81AB-9D0377ABA6CD
P921
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Inhibitor of nuclear factor kappa B kinase subunit gamma
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
@en
type
label
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
@en
altLabel
FIP-3
@en
I-kappa-B kinase subunit gamma
@en
IKBKG
@en
IKK-gamma
@en
IKKAP1
@en
IKKG
@en
Inhibitor of nuclear factor kappa-B kinase subunit gamma
@en
NF-kappa-B essential modifier
@en
NF-kappa-B essential modulator
@en
ikB kinase subunit gamma
@en
prefLabel
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
@en
P527
P637
P638
P680
P681
P682
P705
P352
P637
P31
P352
P527
P637
NP_001093326
NP_001093327
NP_001138727
NP_001308325
NP_001308326
NP_001364241
NP_001364242
NP_001364243
NP_001364244
P638
P680
P681
P682
P702
P703
P705
ENSP00000390368
ENSP00000394934
ENSP00000395205
ENSP00000398579
ENSP00000471166
ENSP00000478616
ENSP00000478979
ENSP00000479144
ENSP00000479662
ENSP00000480431