FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade
about
F-box protein FBXL2 inhibits gastric cancer proliferation by ubiquitin-mediated degradation of forkhead box M1Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.A CULLINary ride across the secretory pathway: more than just secretion.Protein homeostasis of a metastable subproteome associated with Alzheimer's disease.Roles of F-box proteins in cancerSignal transducer and activator of transcription 3 and the phosphatidylinositol 3-kinase regulatory subunits p55α and p50α regulate autophagy in vivo.The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of SurvivinKIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation.Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsFbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5.Mechanisms and function of substrate recruitment by F-box proteins.iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.Oncoprotein stabilization in brain tumors.Genetic alterations of protein tyrosine phosphatases in human cancers.SCF ubiquitin ligase-targeted therapies.Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.The G protein-coupled receptor GPR31 promotes membrane association of KRAS.BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation.NEDD4L Protein Catalyzes Ubiquitination of PIK3CA Protein and Regulates PI3K-AKT Signaling.SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.Recent advances in SCF ubiquitin ligase complex: Clinical implicationsLow-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms.The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells.Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3-kinase (PI3K), p85α and p85β.PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth.A Comprehensive Survey of the Roles of Highly Disordered Proteins in Type 2 Diabetes.Ubiquitin ligases in oncogenic transformation and cancer therapy.The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.Bassoon and piccolo regulate ubiquitination and link presynaptic molecular dynamics with activity-regulated gene expression.The long tail of oncogenic drivers in prostate cancer.Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy.Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System
P2860
00e4eb944c69f48d46c9abc06c68844dfcaf7afd06e059dd5058291800480e40f49ec8c1f56465f734123081f6d69c55eb79a513221a244688ed520f3ee0d60680a9e73b48fb78a987577ce6cf6c4fb65b536adf1322a9ea4e3390411375f0590a4943905c564fb6754845e28786e5f0573af9f2d7a6fb04bbab437f21f1c7533703c6df2106a82ff8f2c28ac2493a34fa9727661123ce4d0073f246b0abb3d9c75ce934d6161233984ea823e09380c9b97a516dd0e80a4cc5872f7aea0d26289ca70dc153e21ac6e37273dc932859d9b58b3628d4a29ef8ae99b097
P248
Q28118130-22435553-14F7-4E09-9599-8549D575CE10Q30278581-EF0DF4B5-60EC-462B-81C4-6F5F9A2AAE33Q33819289-0CA558DD-9E07-4B6C-9235-C785D3A84E56Q33913554-690A1223-95F9-48B6-98A3-AB1977CDBFB4Q35012352-88005D9C-6F5D-4158-99B7-C219ACB6526EQ35190557-FCDF50B8-A8F1-4BAA-985D-0D8DAE21AA9FQ35583027-78886203-C128-4863-BFDE-BD17CCA9AC92Q36148385-A7243F47-AEC0-4757-BFE8-66077F2CE1C3Q36703456-2F311265-19C0-4DBE-A894-C41598B4C099Q36869303-E4D181BD-FFE2-43E1-AB24-1CC51D1552BFQ37307464-29B564DC-3D74-487E-95FB-44D3EA5E1EFCQ37365441-EA4B8ACD-F88D-4489-B402-7BA56204B462Q37369378-E676F44C-57B6-412E-B72F-7DA0D58EC415Q38156100-69DC238A-3ACE-435C-B9CA-30EAFAA59D01Q38255066-257C6CC9-B851-4004-830C-7C2F9115FB73Q38267996-FB2EE7E3-9C30-4226-AA47-A4A0F129F2B6Q38681448-5EBBB185-4016-4BFE-85D4-8A886BADAD3DQ38723395-2B6DF900-84D1-4E07-A730-48BBA4958E32Q38725838-CF5E3D06-3518-468F-86AF-85396B01ACE4Q38762539-5D4A5382-1283-4D94-AD6E-96AB50608D9BQ38768033-4F56D059-62BA-4180-8BA8-1B8A3CDC8FC7Q38828721-AADA9456-2909-4F89-A679-32CA20285388Q39102072-BFED3386-49CA-4BA0-829D-398D12857235Q40285053-1398DDF4-1A49-45A3-A2F5-4B762C117FE4Q41348786-FBE0D8E1-D333-499C-8B6D-79F070A9BC6DQ42280031-9E4DDF57-A8B1-4AE4-B6D5-F79ABFDD43CCQ43283307-8997740E-BEEA-4B80-859C-F819063CBAB9Q46609299-6130AD16-31BB-4B6D-8D0A-A9D4F0DDEED6Q48000346-C0F86747-9502-4305-B7B4-3AB69798900BQ48878407-5542AD56-063B-418E-8ACA-EC08CCF0F041Q52611753-DC9FA3A2-07CC-4696-987B-3D6FCE23C1AAQ54942210-CD3CACCA-6C6B-44FF-9F5A-224E1DFD6CD5Q58586113-0A041722-9787-4DC7-A9E0-F59DFF983C20
P2860
FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@ast
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@en
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@en-gb
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@nl
type
label
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@ast
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@en
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@en-gb
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@nl
prefLabel
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@ast
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@en
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@en-gb
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
FBXL2- and PTPL1-mediated degr ...... the PI(3)K signalling cascade
@en
P2093
Emily Schenkein
Shafi Kuchay
Shanshan Duan
P2860
P2888
P304
P3181
P356
10.1038/NCB2731
P407
P5008
P577
2013-05-01T00:00:00Z
P5875
P6179
1027040720