GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
about
High expression of GOLPH3 in esophageal squamous cell carcinoma correlates with poor prognosisGOLPH3 predicts survival of colorectal cancer patients treated with 5-fluorouracil-based adjuvant chemotherapyGermline mutations in TMEM127 confer susceptibility to pheochromocytomaGolgi phosphoprotein 3 determines cell binding properties under dynamic flow by controlling Golgi localization of core 2 N-acetylglucosaminyltransferase 1.GOLPH3L antagonizes GOLPH3 to determine Golgi morphologyThe tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal functionRegulation of WASH-dependent actin polymerization and protein trafficking by ubiquitinationDNA damage triggers Golgi dispersal via DNA-PK and GOLPH3GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote buddingClinical relevance of SKP2 alterations in metastatic melanomaThe GOLPH3 pathway regulates Golgi shape and function and is activated by DNA damageAdaptive resistance to targeted therapies in cancerGolgi membrane dynamics and lipid metabolismMelanoma: from mutations to medicineSorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelopeDistinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231PtdIns4 P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi traffickingAdapt, Recycle, and Move on: Proteostasis and Trafficking Mechanisms in MelanomaThe multiple cellular functions of the oncoprotein Golgi phosphoprotein 3PITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant SecretionCinderella story: PI4P goes from precursor to key signaling moleculeGenomic aberrations in lung adenocarcinoma in never smokersR-SNARE ykt6 resides in membrane-associated protease-resistant protein particles and modulates cell cycle progression when over-expressedLow dose rapamycin exacerbates autoimmune experimental uveitisiBAG: integrative Bayesian analysis of high-dimensional multiplatform genomics data.Hepatitis C Virus Is Released via a Noncanonical Secretory Route.GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge.Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11.Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants.The N-terminus of Vps74p is essential for the retention of glycosyltransferases in the Golgi but not for the modulation of apical polarized growth in Saccharomyces cerevisiaeGOLPH3 is a novel marker of poor prognosis and a potential therapeutic target in human renal cell carcinoma.Integrative genome comparison of primary and metastatic melanomas.Recurrent hemizygous deletions in cancers may optimize proliferative potentialPhysiological regulation of Akt activity and stability.Insulin and glucagon regulate pancreatic α-cell proliferationMaking sense of cancer genomic data.Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.An oncogenic protein Golgi phosphoprotein 3 up-regulates cell migration via sialylation.Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration.Overexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma.
P2860
Q21134033-4CBB8A28-24C1-4A21-B9DA-1DF27A45D9D9Q21245490-CE0FB3AD-02E2-43E0-B0FE-A4DECFC00225Q24299202-F3CF29D7-252D-43C3-ADBE-C71C8A4F8A04Q24300050-50FFCB93-BF60-4958-BFFD-90987448B840Q24310755-5CDABF04-F63C-43B4-BA25-94D89AB48D75Q24312781-BAF40B3A-9109-49D6-A226-CA5B9153D915Q24321352-352E5B71-270A-4052-B991-3EDA09077D23Q24324801-6ADEE6CD-43BD-4582-8444-4E5AEA000566Q24336708-BC29F848-79BC-4CB4-83E3-9ACAA348F6B4Q24630149-DE4924BF-FF23-499B-9B5B-1FF2155EC410Q26779324-9F6FBDA9-714B-4D5A-8B5C-ED2BA3D1D073Q26849316-0E1E7F4A-28D9-4499-91BB-9A26780B7B3BQ27016562-0B367821-9A10-47CC-B508-015BBAC02FCEQ27024061-D651D6F3-CC1C-4A10-8B17-B3D925F66D1CQ27319479-13617D0C-249F-4AFB-B0D2-85D3D4BDD7E5Q27348648-B3D3002A-1209-4114-8D88-E4383AE89D5EQ27658740-CD818D85-CC19-4E52-8718-E25FFDAACF04Q28069018-BDF64D08-59ED-4E59-BDD9-ACF5A42FE7CFQ28082896-CB1B5657-5482-47DD-AC27-6293D5821869Q28118950-357033E0-DBE0-4088-AB70-0E73DA216118Q28301748-5A41C718-68B4-4F73-95BD-29CA15A635C1Q28385032-2FB3DE84-650A-4EAE-AD5D-5FD871C80DBCQ28580997-16ECFE6C-7670-48FD-8BE4-A33BF2354424Q28730115-F43DD478-CB6C-4B82-A386-A82EE921AFB9Q30577081-B8DEFC12-0D51-42CB-9CCB-4ED11E21CA76Q30828742-BA283EE2-4238-445B-B98D-9297199A2918Q30832460-B0CD5BDF-5EE1-4AA4-BDB2-B26045EEB863Q30833421-4454DAA9-7D3C-4C9E-BE92-90E9937F99C1Q31105539-C0EE3896-35F7-4F37-916B-FBB0FE23FFC8Q31138110-D9587B77-DD03-4C36-A200-B59839FDF4A4Q33555212-7F2C92D0-C319-447D-A1EA-1CD562AA7C38Q33592837-172A1C39-0978-488A-9267-636CDC380645Q33637152-B56EC47F-A723-4A29-B7BD-A943A7E8F502Q33680673-B837573B-9C9C-4034-B644-2F04431F96D2Q33808713-47F5F98C-A34F-45BB-AFE3-98D14891D494Q33846850-1FAB45CA-FB82-44C2-B245-7646154D87C7Q33848827-90E59702-9C0E-4FED-9DC2-478589AC0E65Q33947085-44BD37B8-80E1-4C1C-8AFD-CFD1A0B4815CQ33991769-E4BCB078-6F30-4690-838C-DD25229834E2Q34048461-39D8379A-254C-4FB3-B3BE-FC843565FEBD
P2860
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@ast
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@en
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@en-gb
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@nl
type
label
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@ast
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@en
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@en-gb
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@nl
prefLabel
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@ast
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@en
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@en-gb
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@nl
P2093
P2860
P3181
P356
P1433
P1476
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
@en
P2093
Abdel Saci
Alexei Protopopov
David E Fisher
David L Rimm
Elena Ivanova
Hans R Widlund
Joseph Huang
Kenneth L Scott
Mei-Chih Liang
P2860
P2888
P304
P3181
P356
10.1038/NATURE08109
P407
P577
2009-06-25T00:00:00Z
P5875
P6179
1043238674