Integrative genome comparison of primary and metastatic melanomas.
about
Proinvasion metastasis drivers in early-stage melanoma are oncogenes.Exome sequencing identifies recurrent somatic RAC1 mutations in melanomaThyroid Growth and CancerProtein kinase A activity and anchoring are required for ovarian cancer cell migration and invasionPhylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination.SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells.The best of both worlds - managing the cancer, saving the bone.P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.Genomics screens for metastasis genesLoss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanomaMolecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic targetAn attempt at a molecular prediction of metastasis in patients with primary cutaneous melanoma.Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells.Integrative genomics identifies gene signature associated with melanoma ulceration.Superficial spreading and nodular melanoma are distinct biological entities: a challenge to the linear progression model.MALAT1 promotes colorectal cancer cell proliferation/migration/invasion via PRKA kinase anchor protein 9.ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survivalA genomic approach to study down syndrome and cancer inverse comorbidity: untangling the chromosome 21.Identification of candidate driver genes in common focal chromosomal aberrations of microsatellite stable colorectal cancerSds22/PP1 links epithelial integrity and tumor suppression via regulation of myosin II and JNK signalingFBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification.The metastasis suppressor NME1 regulates expression of genes linked to metastasis and patient outcome in melanoma and breast carcinoma.Metastasis suppressor NME1 regulates melanoma cell morphology, self-adhesion and motility via induction of fibronectin expressionGenome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker over-expressed in cancer.Human melanoma metastasis in NSG mice correlates with clinical outcome in patients.ZBTB7A Suppresses Melanoma Metastasis by Transcriptionally Repressing MCAM.Centrosomal AKAP350 and CIP4 act in concert to define the polarized localization of the centrosome and Golgi in migratory cellsLoss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis.Analysis of molecular intra-patient variation and delineation of a prognostic 12-gene signature in non-muscle invasive bladder cancer; technology transfer from microarrays to PCR.BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistanceClear cell carcinomas of the ovary: a mono-institutional study of 73 cases in China with an analysis of the prognostic significance of clinicopathological parameters and IMP3 expression.Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cells.AKAP-9 promotes colorectal cancer development by regulating Cdc42 interacting protein 4.IgG subclass switching and clonal expansion in cutaneous melanoma and normal skinSynergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma.Thin and thick primary cutaneous melanomas reveal distinct patterns of somatic copy number alterations.microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance.
P2860
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P2860
Integrative genome comparison of primary and metastatic melanomas.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Integrative genome comparison of primary and metastatic melanomas.
@ast
Integrative genome comparison of primary and metastatic melanomas.
@en
type
label
Integrative genome comparison of primary and metastatic melanomas.
@ast
Integrative genome comparison of primary and metastatic melanomas.
@en
prefLabel
Integrative genome comparison of primary and metastatic melanomas.
@ast
Integrative genome comparison of primary and metastatic melanomas.
@en
P2093
P2860
P50
P1433
P1476
Integrative genome comparison of primary and metastatic melanomas.
@en
P2093
Carlos Cordon-Cardo
Kenneth L Scott
Lawrence N Kwong
Lyn M Duncan
Marcus Bosenberg
Omar Kabbarah
Scott R Granter
Sridhar Ramaswamy
P2860
P304
P356
10.1371/JOURNAL.PONE.0010770
P407
P577
2010-05-24T00:00:00Z