Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage - Test2 - elhamkhani - TriplyDB

Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage

Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage

http://www.wikidata.org/entity/Q24537734

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AKT/PKB signaling: navigating downstream The phosphoinositide 3-kinase pathway and therapy resistance in cancer hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling Chromium genotoxicity: A double-edged sword Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency PPARδ regulates satellite cell proliferation and skeletal muscle regeneration The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase 1 Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling.MicroRNA-101-mediated Akt activation and estrogen-independent growth.Signaling specificity in the Akt pathway in biology and disease.Akt activation emulates Chk1 inhibition and Bcl2 overexpression and abrogates G2 cell cycle checkpoint by inhibiting BRCA1 foci 3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.Akt: a double-edged sword in cell proliferation and genome stability.siRNA-mediated downregulation of MMP-9 and uPAR in combination with radiation induces G2/M cell-cycle arrest in Medulloblastoma.Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells.Human phosphatidylethanolamine-binding protein 4 promoted the radioresistance of human rectal cancer by activating Akt in an ROS-dependent way.Glucose metabolism measured by [¹⁸F]fluorodeoxyglucose positron emission tomography is independent of PTEN/AKT status in human colon carcinoma cells.Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation by Inhibiting AKT Signaling.CaCO₃/CaIP₆ composite nanoparticles effectively deliver AKT1 small interfering RNA to inhibit human breast cancer growth.Novel naphthochalcone derivative accelerate dermal wound healing through induction of epithelial-mesenchymal transition of keratinocyte.Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells.Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation.Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis.Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells.Protein kinase A type II-α regulatory subunit regulates the response of prostate cancer cells to taxane treatment.Expression of phosphorylated mTOR and its regulatory protein is related to biological behaviors of ameloblastoma.Juglanthraquinone C Induces Intracellular ROS Increase and Apoptosis by Activating the Akt/Foxo Signal Pathway in HCC Cells.Nutrient restriction and radiation therapy for cancer treatment: when less is more An IGF1/insulin receptor substrate-1 pathway stimulates a mitotic kinase (cdk1) in the uterine epithelium during the proliferative response to estradiol.Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation Temozolomide in combination with metformin act synergistically to inhibit proliferation and expansion of glioma stem-like cells.Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma.Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein induce Akt phosphorylation in the ischemic brain Degradation of Akt using protein-catalyzed capture agents.The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents Caloric restriction augments radiation efficacy in breast cancer.

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Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage

http://www.wikidata.org/entity/Q24537734

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2002 nî lūn-bûn

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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

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2002年论文

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name

Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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type

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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MCB.22.22.7831-7841.2002

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Molecular and Cellular Biology

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Activation of Akt/protein kina ...... eckpoint induced by DNA damage

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Andrei Gartel

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Antonio Di Cristofano

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Claudine S Feliciano

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Eugene S Kandel

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Jennifer Skeen

http://www.w3.org/2001/XMLSchema#string

Nathan Majewski

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Nissim Hay

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P2860

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells

PTEN: life as a tumor suppressor

Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

Pten is essential for embryonic development and tumour suppression

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

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7831-41

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scholarly article

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4436924

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10.1128/MCB.22.22.7831-7841.2002

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22

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22

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Pier Paolo Pandolfi

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2002-11-01T00:00:00Z

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5440257

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12391152

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134727

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