A role of PDGFRalpha in basal cell carcinoma proliferation - Test2 - elhamkhani - TriplyDB

A role of PDGFRalpha in basal cell carcinoma proliferation

A role of PDGFRalpha in basal cell carcinoma proliferation

http://www.wikidata.org/entity/Q24555827

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NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells Activation of the hedgehog pathway in advanced prostate cancer Profile of nintedanib in the treatment of solid tumors: the evidence to date Structural and functional properties of platelet-derived growth factor and stem cell factor receptors Glucose transport: meeting the metabolic demands of cancer, and applications in glioblastoma treatment The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.Toll-like receptor 3 regulates neural stem cell proliferation by modulating the Sonic Hedgehog pathway.Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft Transactivation of platelet-derived growth factor receptor alpha by the GTPase-deficient activated mutant of Galpha12.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Targeting the PDGF signaling pathway in tumor treatment Basal cell carcinoma: from the molecular understanding of the pathogenesis to targeted therapy of progressive disease.Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.Clinical implications of hedgehog signaling pathway inhibitors Identification of signature genes for detecting hedgehog signaling activation in gastric cancer.Identification of signature genes for detecting hedgehog pathway activation in esophageal cancer.Basal cell carcinomas: attack of the hedgehog.Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosis.MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1.A Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction.Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.The Hedgehog pathway: role in cell differentiation, polarity and proliferation Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway.A role for transcription factor STAT3 signaling in oncogene smoothened-driven carcinogenesis.ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.Versican: signaling to transcriptional control pathways.Hedgehog signalling in skin development and cancer.Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.Implications of hedgehog signaling antagonists for cancer therapy.G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation.Combining hedgehog signaling inhibition with focal irradiation on reduction of pancreatic cancer metastasis.Targeting hedgehog signaling in cancer: research and clinical developments.A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway

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A role of PDGFRalpha in basal cell carcinoma proliferation

http://www.wikidata.org/entity/Q24555827

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2001 nî lūn-bûn

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2001年の論文

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A role of PDGFRalpha in basal cell carcinoma proliferation

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A role of PDGFRalpha in basal cell carcinoma proliferation

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A role of PDGFRalpha in basal cell carcinoma proliferation

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A role of PDGFRalpha in basal cell carcinoma proliferation

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A role of PDGFRalpha in basal cell carcinoma proliferation

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A role of PDGFRalpha in basal cell carcinoma proliferation

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prefLabel

A role of PDGFRalpha in basal cell carcinoma proliferation

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A role of PDGFRalpha in basal cell carcinoma proliferation

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A role of PDGFRalpha in basal cell carcinoma proliferation

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Proceedings of the National Academy of Sciences of the United States of America

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A role of PDGFRalpha in basal cell carcinoma proliferation

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C Zachary

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E Epstein

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F McCormick

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J M Bonifas

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P2860

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli

Activating Smoothened mutations in sporadic basal-cell carcinoma

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system

Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

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10.1073/PNAS.151173398

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