The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor - Test2 - elhamkhani - TriplyDB

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists Structure of an agonist-bound human A2A adenosine receptor Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor The Use of Multiscale Molecular Simulations in Understanding a Relationship between the Structure and Function of Biological Systems of the Brain: The Application to Monoamine Oxidase Enzymes Biased and g protein-independent signaling of chemokine receptors Systems pharmacology: network analysis to identify multiscale mechanisms of drug action Post-expression strategies for structural investigations of membrane proteins.Diversity and modularity of G protein-coupled receptor structures Large-scale production and protein engineering of G protein-coupled receptors for structural studies New insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptors Molecular Evolution and Functional Divergence of Trace Amine-Associated Receptors Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine Structure of the agonist-bound neurotensin receptor Crystal Structure of the Complex mAb 17.2 and the C-Terminal Region of Trypanosoma cruzi P2β Protein: Implications in Cross-Reactivity Crystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal state Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor Agonist-bound structure of the human P2Y12 receptor Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs Nanobody stabilization of G protein-coupled receptor conformational states.Full and Partial Agonism of a Designed Enzyme Switch Multiple conformational states in retrospective virtual screening – homology models vs. crystal structures: beta-2 adrenergic receptor case study Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors Generic GPCR residue numbers - aligning topology maps while minding the gaps Simple screening method for improving membrane protein thermostability Function-specific virtual screening for GPCR ligands using a combined scoring method Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor GOMoDo: A GPCRs online modeling and docking webserver Lipid receptor S1P₁ activation scheme concluded from microsecond all-atom molecular dynamics simulations 3D structure prediction of human β1-adrenergic receptor via threading-based homology modeling for implications in structure-based drug designing Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysis Beyond small-molecule SAR: using the dopamine D3 receptor crystal structure to guide drug design A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102)The role of experimental and computational structural approaches in 7TM drug discovery.Mechanism of allosteric regulation of β2-adrenergic receptor by cholesterol.Investigation of D₂ receptor-agonist interactions using a combination of pharmacophore and receptor homology modeling.

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

http://www.wikidata.org/entity/Q24594844

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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type

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

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Andrew G W Leslie

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Patricia C Edwards

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Rony Nehmé

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Rouslan Moukhametzianov

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P2860

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

Crystal structure of the ligand-free G-protein-coupled receptor opsin

Structure of a beta1-adrenergic G-protein-coupled receptor.

Crystal structure of opsin in its G-protein-interacting conformation

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

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241-244

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scholarly article

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499166

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10.1038/NATURE09746

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7329

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469

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Christopher G. Tate

Jillian G Baker

Gebhard Schertler

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2011-01-01T00:00:00Z

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49749524

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1047634683

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21228877

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3023143

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