Structure of an agonist-bound human A2A adenosine receptor
about
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activationCrystal structure of a lipid G protein-coupled receptorStructure of the human κ-opioid receptor in complex with JDTicStructure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulatorStructure of the human histamine H1 receptor complex with doxepinAdenosine and hypoxia-inducible factor signaling in intestinal injury and recoveryStructural Studies of G Protein-Coupled ReceptorsPurinergic signalling and diabetesDiversity and modularity of G protein-coupled receptor structuresLarge-scale production and protein engineering of G protein-coupled receptors for structural studiesNew insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptorsCommunication over the network of binary switches regulates the activation of A2A adenosine receptorA new drug design targeting the adenosinergic system for Huntington's diseaseCrystal structure of rhodopsin bound to arrestin by femtosecond X-ray laserStructural Basis for Allosteric Regulation of GPCRs by Sodium IonsStructure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and CaffeineCrystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal stateBiophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug DesignStructural Features for Functional Selectivity at Serotonin ReceptorsG-protein-coupled receptor inactivation by an allosteric inverse-agonist antibodyCrystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and CarvedilolAdrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobodyMolecular control of δ-opioid receptor signallingThe 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free ReceptorAgonist-bound structure of the human P2Y12 receptorStructural basis for Smoothened receptor modulation and chemoresistance to anticancer drugsNanobody stabilization of G protein-coupled receptor conformational states.Activation mechanism of endothelin ETB receptor by endothelin-1Multiple conformational states in retrospective virtual screening – homology models vs. crystal structures: beta-2 adrenergic receptor case studySimple screening method for improving membrane protein thermostabilityFunction-specific virtual screening for GPCR ligands using a combined scoring methodInsights into the molecular evolution of oxytocin receptor ligand bindingActivation biosensor for G protein-coupled receptors: a FRET-based m1 muscarinic activation sensor that regulates G(q)Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congenersStructural and energetic effects of A2A adenosine receptor mutations on agonist and antagonist bindingStructure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional ImplicationsAn Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase ActivityEffects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signallingAdenosine receptors as drug targets--what are the challenges?Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes.
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P2860
Structure of an agonist-bound human A2A adenosine receptor
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structure of an agonist-bound human A2A adenosine receptor
@ast
Structure of an agonist-bound human A2A adenosine receptor
@en
Structure of an agonist-bound human A2A adenosine receptor
@en-gb
Structure of an agonist-bound human A2A adenosine receptor
@nl
type
label
Structure of an agonist-bound human A2A adenosine receptor
@ast
Structure of an agonist-bound human A2A adenosine receptor
@en
Structure of an agonist-bound human A2A adenosine receptor
@en-gb
Structure of an agonist-bound human A2A adenosine receptor
@nl
altLabel
Structure of an Agonist-Bound Human A2A Adenosine Receptor
@en
prefLabel
Structure of an agonist-bound human A2A adenosine receptor
@ast
Structure of an agonist-bound human A2A adenosine receptor
@en
Structure of an agonist-bound human A2A adenosine receptor
@en-gb
Structure of an agonist-bound human A2A adenosine receptor
@nl
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Structure of an agonist-bound human A2A adenosine receptor
@en
P2093
Gye Won Han
Raymond C Stevens
Vadim Cherezov
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P304
P3181
P356
10.1126/SCIENCE.1202793
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P577
2011-03-10T00:00:00Z