Structure of the human histamine H1 receptor complex with doxepin
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Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNTStructure of the human κ-opioid receptor in complex with JDTicStructure of the human M2 muscarinic acetylcholine receptor bound to an antagonistCrystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptorG Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsEngineering therapeutic antibodies targeting G-protein-coupled receptorsStructural Studies of G Protein-Coupled ReceptorsInternational Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsPost-expression strategies for structural investigations of membrane proteins.Diversity and modularity of G protein-coupled receptor structuresLarge-scale production and protein engineering of G protein-coupled receptors for structural studiesNew insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptorsComputational approaches for modeling GPCR dimerizationFluorescent approaches for understanding interactions of ligands with G protein coupled receptorsTools for GPCR drug discovery.Endogenous lipid activated G protein-coupled receptors: emerging structural features from crystallography and molecular dynamics simulationsCardiac contractility structure-activity relationship and ligand-receptor interactions; the discovery of unique and novel molecular switches in myosuppressin signalingMembrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCRN-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled ReceptorStructural Characterization of an LPA1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding ConstraintCrystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal stateBiophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug DesignG-protein-coupled receptor inactivation by an allosteric inverse-agonist antibodySolid-state NMR spectroscopy structure determination of a lipid-embedded heptahelical membrane proteinNanobody stabilization of G protein-coupled receptor conformational states.Multiple conformational states in retrospective virtual screening – homology models vs. crystal structures: beta-2 adrenergic receptor case studyTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsGeneric GPCR residue numbers - aligning topology maps while minding the gapsFunction-specific virtual screening for GPCR ligands using a combined scoring methodInsights into the molecular evolution of oxytocin receptor ligand bindingModeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugsAssessment and challenges of ligand docking into comparative models of G-protein coupled receptorsRecombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranesSequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonismStructure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional ImplicationsSequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysisTP Atlas: integration and dissemination of advances in Targeted Proteins Research Program (TPRP)-structural biology project phase II in JapanMolecular evolution of a peptide GPCR ligand driven by artificial neural networksLipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR.Antihistamine response: a dynamically refined function at the host-tick interface.
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P2860
Structure of the human histamine H1 receptor complex with doxepin
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structure of the human histamine H1 receptor complex with doxepin
@ast
Structure of the human histamine H1 receptor complex with doxepin
@en
Structure of the human histamine H1 receptor complex with doxepin
@nl
type
label
Structure of the human histamine H1 receptor complex with doxepin
@ast
Structure of the human histamine H1 receptor complex with doxepin
@en
Structure of the human histamine H1 receptor complex with doxepin
@nl
prefLabel
Structure of the human histamine H1 receptor complex with doxepin
@ast
Structure of the human histamine H1 receptor complex with doxepin
@en
Structure of the human histamine H1 receptor complex with doxepin
@nl
P2093
P2860
P50
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P1476
Structure of the human histamine H1 receptor complex with doxepin
@en
P2093
Graeme Winter
Gye Won Han
Hirokazu Tsujimoto
Mitsunori Shiroishi
Raymond C Stevens
Simone Weyand
Takuya Kobayashi
Tatsuro Shimamura
P2860
P2888
P3181
P356
10.1038/NATURE10236
P407
P577
2011-07-07T00:00:00Z
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P6179
1040196439