The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells
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PARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neuronsFBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like ModifiersBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δA fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.Increased Anticancer Efficacy of Intravesical Mitomycin C Therapy when Combined with a PCNA Targeting Peptide.Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases.Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.Protein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stabilityPCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication StressMismatch repair proteins recruited to ultraviolet light-damaged sites lead to degradation of licensing factor Cdt1 in the G1 phase.The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants.PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damageTwo-way communications between ubiquitin-like modifiers and DNA.Enhanced efficacy of bleomycin in bladder cancer cells by photochemical internalization.Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.Regulation and Modulation of Human DNA Polymerase δ Activity and Function.Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans.Rare FBXO18 variations and risk of schizophrenia: Whole-exome sequencing in two parent-affected offspring trios followed by resequencing and case-control studies.The translesion DNA polymerases Pol ζ and Rev1 are activated independently of PCNA ubiquitination upon UV radiation in mutants of DNA polymerase δ.APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer.Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy.Involvement of SPATA31 copy number variable genes in human lifespan.The role of PCNA as a scaffold protein in cellular signaling is functionally conserved between yeast and humans."Two hits - one stone"; increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling
P2860
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P2860
The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells
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2013 nî lūn-bûn
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2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
@zh-hk
2013年論文
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2013年論文
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2013年论文
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The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@ast
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@en
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@nl
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label
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@ast
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@en
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@nl
prefLabel
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@ast
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@en
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@nl
P2093
P2860
P3181
P356
P1476
The helicase FBH1 is tightly r ...... ted proteolysis in human cells
@en
P2093
Agathe Bacquin
Carine Tellier-Lebegue
Caroline Pouvelle
Mylène Perderiset
Nicolas Siaud
Patricia L Kannouche
Sophie Salomé-Desnoulez
P2860
P304
P3181
P356
10.1093/NAR/GKT397
P407
P577
2013-05-15T00:00:00Z