FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress
about
FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cellsThe helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cellsTargeting the Checkpoint to Kill Cancer CellsSrs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes.DNA helicases involved in DNA repair and their roles in cancerEXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele.Cataloging antineoplastic agents according to their effectiveness against platinum-resistant and platinum-sensitive ovarian carcinoma cell lines.Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing.The Intra-S Checkpoint Responses to DNA Damage.PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damageResolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes.Replication fork reversal in eukaryotes: from dead end to dynamic response.Substrate specificity of the MUS81-EME2 structure selective endonuclease.MUS81-EME2 promotes replication fork restart.Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage.Death becomes her: FBH1, DNA damage and apoptosis.SLX4 gains weight with SUMO in genome maintenance.FBH1: a new checkpoint factor.The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation.ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair.Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.Complex repeat structure promotes hyper-amplification and amplicon evolution through rolling-circle replication.Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress.
P2860
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P248
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P2860
FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
FBH1 co-operates with MUS81 in ...... h following replication stress
@ast
FBH1 co-operates with MUS81 in ...... h following replication stress
@en
FBH1 co-operates with MUS81 in ...... h following replication stress
@en-gb
FBH1 co-operates with MUS81 in ...... h following replication stress
@nl
type
label
FBH1 co-operates with MUS81 in ...... h following replication stress
@ast
FBH1 co-operates with MUS81 in ...... h following replication stress
@en
FBH1 co-operates with MUS81 in ...... h following replication stress
@en-gb
FBH1 co-operates with MUS81 in ...... h following replication stress
@nl
prefLabel
FBH1 co-operates with MUS81 in ...... h following replication stress
@ast
FBH1 co-operates with MUS81 in ...... h following replication stress
@en
FBH1 co-operates with MUS81 in ...... h following replication stress
@en-gb
FBH1 co-operates with MUS81 in ...... h following replication stress
@nl
P2093
P2860
P50
P921
P356
P1476
FBH1 co-operates with MUS81 in ...... h following replication stress
@en
P2093
Halfdan Beck
Ian D Hickson
Wai Kit Chu
P2860
P2888
P356
10.1038/NCOMMS2395
P407
P577
2013-01-01T00:00:00Z
P5875
P6179
1018705793