p53-mediated apoptosis is attenuated in Werner syndrome cells - Test2 - elhamkhani - TriplyDB

p53-mediated apoptosis is attenuated in Werner syndrome cells

p53-mediated apoptosis is attenuated in Werner syndrome cells

http://www.wikidata.org/entity/Q24603148

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Werner Syndrome p53 Modulates the exonuclease activity of Werner syndrome protein Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth control Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged bases Physical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferase Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1 The spectrum of WRN mutations in Werner syndrome patients POT1 and TRF2 cooperate to maintain telomeric integrity The RecQ DNA helicases in DNA repair Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A Roles of Werner syndrome protein in protection of genome integrity Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromes Werner protein recruits DNA polymerase delta to the nucleolus Human premature aging, DNA repair and RecQ helicases A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice Crystal structure of the HRDC domain of human Werner syndrome protein, WRN p53 in the DNA-Damage-Repair Process Functional interaction of p53 and BLM DNA helicase in apoptosis Regulation of the Werner helicase through a direct interaction with a subunit of protein kinase A Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation The processing of Holliday junctions by BLM and WRN helicases is regulated by p53 A novel protein interacts with the Werner's syndrome gene product physically and functionally Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer Mutations in the WRN gene in mice accelerate mortality in a p53-null background Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1 RecQ helicases: caretakers of the genome Redundancy of DNA helicases in p53-mediated apoptosis.Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue.Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.Physical and functional interaction between p53 and the Werner's syndrome protein.Functional interaction between the Werner Syndrome protein and DNA polymerase delta Definition of the p53 functional domains necessary for inducing apoptosis.Differential regulation of human RecQ family helicases in cell transformation and cell cycle.Interactions of DNA helicases with damaged DNA: possible biological consequences.RecQ helicases: at the heart of genetic stability.Characterization of the DNA-unwinding activity of human RECQ1, a helicase specifically stimulated by human replication protein A.Monogenic syndromes of abnormal glucose homeostasis: clinical review and relevance to the understanding of the pathology of insulin resistance and beta cell failure.

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p53-mediated apoptosis is attenuated in Werner syndrome cells

http://www.wikidata.org/entity/Q24603148

description

1999 nî lūn-bûn

@nan

1999 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հունիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

p53-mediated apoptosis is attenuated in Werner syndrome cells

@ast

p53-mediated apoptosis is attenuated in Werner syndrome cells

@en

p53-mediated apoptosis is attenuated in Werner syndrome cells

@nl

type

label

p53-mediated apoptosis is attenuated in Werner syndrome cells

@ast

p53-mediated apoptosis is attenuated in Werner syndrome cells

@en

p53-mediated apoptosis is attenuated in Werner syndrome cells

@nl

prefLabel

p53-mediated apoptosis is attenuated in Werner syndrome cells

@ast

p53-mediated apoptosis is attenuated in Werner syndrome cells

@en

p53-mediated apoptosis is attenuated in Werner syndrome cells

@nl

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Genes & Development

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p53-mediated apoptosis is attenuated in Werner syndrome cells

@en

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A I Robles

http://www.w3.org/2001/XMLSchema#string

C C Harris

http://www.w3.org/2001/XMLSchema#string

C E Yu

http://www.w3.org/2001/XMLSchema#string

E A Spillare

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G D Schellenberg

http://www.w3.org/2001/XMLSchema#string

J C Shen

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X W Wang

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P2860

The Werner syndrome protein is a DNA helicase

Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

Nucleolar localization of the Werner syndrome protein in human cells

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

p53 modulation of TFIIH-associated nucleotide excision repair activity

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

p53, the cellular gatekeeper for growth and division

Excess of rare cancers in Werner syndrome (adult progeria)

p53 mutations in human cancers

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

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1355-60

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scholarly article

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10.1101/GAD.13.11.1355

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11

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13

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1999-06-01T00:00:00Z

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12935164

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P698

10364153

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P921

apoptotic process

P932

316776

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