about
Different quaternary structures of human RECQ1 are associated with its dual enzymatic activityComplete sequence and comparative genome analysis of the dairy bacterium Streptococcus thermophilusRECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progressionStructural and functional analyses of disease-causing missense mutations in Bloom syndrome proteinRECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombinationStimulation of flap endonuclease-1 by the Bloom's syndrome proteinPhysical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicasesPOT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substratesSenataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damageWerner syndrome protein interacts functionally with translesion DNA polymerasesHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D)The spectrum of WRN mutations in Werner syndrome patientsSws1 is a conserved regulator of homologous recombination in eukaryotic cellsThe HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stressRecql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers.Ddx42p--a human DEAD box protein with RNA chaperone activities.BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesMPS1-dependent mitotic BLM phosphorylation is important for chromosome stabilityHuman RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptidePhysical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein AHomologous recombination in DNA repair and DNA damage toleranceShelterin complex and associated factors at human telomeresMus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cellsUp-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaksThe BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutationsRNA interference inhibition of Mus81 reduces mitotic recombination in human cellsModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingMore complexity to the Bloom's syndrome complexThe Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase deltaManipulating mitotic recombination in the zebrafish embryo through RecQ helicasesHuman RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication forkRECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filamentsFunctional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrestHuman premature aging, DNA repair and RecQ helicasesThe Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNAThe interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNAArchaeal Hel308 helicase targets replication forks in vivo and in vitro and unwinds lagging strands
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
RecQ helicases: caretakers of the genome
@ast
RecQ helicases: caretakers of the genome
@en
type
label
RecQ helicases: caretakers of the genome
@ast
RecQ helicases: caretakers of the genome
@en
prefLabel
RecQ helicases: caretakers of the genome
@ast
RecQ helicases: caretakers of the genome
@en
P2860
P3181
P356
P1476
RecQ helicases: caretakers of the genome
@en
P2093
Hickson ID
P2860
P2888
P304
P3181
P356
10.1038/NRC1012
P407
P577
2003-03-01T00:00:00Z
P6179
1006173489