Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
about
Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombinationRNF4 interacts with both SUMO and nucleosomes to promote the DNA damage responseThe E3 ligase RNF8 regulates KU80 removal and NHEJ repairRNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sitesThe SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARAHuman RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaksDNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancersEpigenetic modifications in double-strand break DNA damage signaling and repairDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsPIAS3 promotes homology‑directed repair and distal non‑homologous end joiningWriters, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairChoreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear ArchitectureInterplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic StressHow SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair PathwayReal Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand BreaksCooperativity of the SUMO and Ubiquitin Pathways in Genome StabilityRoles for SUMO in pre-mRNA processingDouble-strand break repair on sex chromosomes: challenges during male meiotic prophasePredictive models for customizing chemotherapy in advanced non-small cell lung cancer (NSCLC)Repair of strand breaks by homologous recombinationCrosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repairThe DNA Damage Response: Making It Safe to Play with KnivesThe SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition.NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple MyelomaSUMO-mediated regulation of DNA damage repair and responsesSystematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repairmRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancerA viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defenceHistone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatidSUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damageProtein inhibitor of activated STAT 1 (PIAS1) is identified as the SUMO E3 ligase of CCAAT/enhancer-binding protein β (C/EBPβ) during adipogenesisSUMO-specific protease 2 in Mdm2-mediated regulation of p53G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 statusTranscription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α.Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1.BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.SUMOylation inhibits FOXM1 activity and delays mitotic transition.Confinement and deformation of single cells and their nuclei inside size-adapted microtubesSUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway
P2860
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P2860
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@ast
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@en
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@nl
type
label
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@ast
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@en
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@nl
prefLabel
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@ast
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@en
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
@en
P2093
Julia Coates
Kyle M Miller
Rimma Belotserkovskaya
P2860
P2888
P3181
P356
10.1038/NATURE08657
P407
P577
2009-12-17T00:00:00Z
P5875
P6179
1046919299