Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat - Test2 - elhamkhani - TriplyDB

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

http://www.wikidata.org/entity/Q24609782

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Disease-modifying therapeutic directions for Lewy-Body dementias Developing stem cell therapies for juvenile and adult-onset Huntington's disease Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease Self-propagation of pathogenic protein aggregates in neurodegenerative diseases Proteolytic clearance of extracellular α-synuclein as a new therapeutic approach against Parkinson disease Inflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link?Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease Spreading of pathology in neurodegenerative diseases: a focus on human studies Alpha-synuclein spreading in Parkinson's disease Role of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative Diseases Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy Exploring Braak's Hypothesis of Parkinson's Disease.Transmission of Synucleinopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice The Interplay between Alpha-Synuclein Clearance and Spreading Frontal cortex neuropathology in dementia pugilistica.Corruption and spread of pathogenic proteins in neurodegenerative diseases.Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease α-Synuclein oligomers and clinical implications for Parkinson disease.Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons.Prion-like propagation of protein aggregation and related therapeutic strategies.Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission.Nanomechanical properties of distinct fibrillar polymorphs of the protein α-synuclein.Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons.Interaction between pathogenic proteins in neurodegenerative disorders.The immunological challenges of cell transplantation for the treatment of Parkinson's disease.Parkinson's disease and parkinsonism: neuropathology.What's to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease?Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder?α-Synuclein: the long distance runner.Loss of functional alpha-synuclein: a toxic event in Parkinson's disease?Potential of Cellular and Animal Models Based on a Prion-Like Propagation of α-Synuclein for Assessing Antiparkinson Agents.Prion-like mechanisms in the pathogenesis of tauopathies and synucleinopathies.Is Parkinson's disease truly a prion-like disorder? An appraisal of current evidence.Alpha-synuclein propagation: New insights from animal models.Review: Parkinson's disease: from synaptic loss to connectome dysfunction.Review: Spreading the word: precise animal models and validated methods are vital when evaluating prion-like behaviour of alpha-synuclein.Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type

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P2860

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

http://www.wikidata.org/entity/Q24609782

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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type

label

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

@nl

prefLabel

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

@en

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

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J.NBD.2011.05.001

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Neurobiology of Disease

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

@en

P2093

Adam M Kordower

http://www.w3.org/2001/XMLSchema#string

Brian Terpstra

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Caryl Sortwell

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Hemraj B Dodiya

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Katrina Paumier

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Lalitha Madhavan

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Timothy J Collier

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P2860

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells.

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

Prion-like transmission of protein aggregates in neurodegenerative diseases

Effect of levodopa priming on dopamine neuron transplant efficacy and induction of abnormal involuntary movements in parkinsonian rats

Research in motion: the enigma of Parkinson's disease pathology spread.

Lewy body pathology in fetal grafts.

Are synucleinopathies prion-like disorders?

Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

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552-7

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scholarly article

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10.1016/J.NBD.2011.05.001

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Kathy Steece-Collier

Jeffrey H Kordower

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2011-09-01T00:00:00Z

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51154618

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21600984

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3430516

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