Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.
about
Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein.Group II mGluRs modulate baseline and arthritis pain-related synaptic transmission in the rat medial prefrontal cortex.Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents.Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2.Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes.Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models.Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate ReceptorsMolecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding.PTSD-Related Behavioral Traits in a Rat Model of Blast-Induced mTBI Are Reversed by the mGluR2/3 Receptor Antagonist BCI-838.
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P2860
Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@ast
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@en
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@nl
type
label
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@ast
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@en
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@nl
prefLabel
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@ast
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@en
Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@nl
P2093
P2860
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Proneurogenic Group II mGluR a ...... n Alzheimer Aβ oligomer mouse.
@en
P2093
G D Clemenson
J W Steele
M E Ehrlich
P2860
P2888
P304
P356
10.1038/MP.2014.87
P407
P577
2014-08-12T00:00:00Z
P5875
P6179
1008451773