A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions
about
Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosisPrion diseases: immunotargets and therapyPrion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseThe role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseasesPathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisSelf-propagation of pathogenic protein aggregates in neurodegenerative diseasesTherapeutic and diagnostic challenges for frontotemporal dementiaNeurodegenerative diseases: expanding the prion conceptPrion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic targetFrontotemporal dementia: a bridge between dementia and neuromuscular diseaseSpreading of pathology in neurodegenerative diseases: a focus on human studiesLegal but lethal: functional protein aggregation at the verge of toxicityPrion-like Mechanism in Amyotrophic Lateral Sclerosis: are Protein Aggregates the Key?New insights into in vitro amyloidogenic properties of human serum albumin suggest considerations for therapeutic precautionsA 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degenerationNovel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins.Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis.The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.Conserved acidic amino acid residues in a second RNA recognition motif regulate assembly and function of TDP-43.Inhibition of TDP-43 aggregation by nucleic acid bindingTargeting RNA binding proteins involved in neurodegeneration.Casein kinase II induced polymerization of soluble TDP-43 into filaments is inhibited by heat shock proteins.Self-propagative replication of Aβ oligomers suggests potential transmissibility in Alzheimer disease.Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis.A yeast functional screen predicts new candidate ALS disease genesGains or losses: molecular mechanisms of TDP43-mediated neurodegeneration.Studies of alternative isoforms provide insight into TDP-43 autoregulation and pathogenesisTargeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice.Corruption and spread of pathogenic proteins in neurodegenerative diseases.Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons.Amyotrophic lateral sclerosis and organ donation: is there risk of disease transmission?Prions and the potential transmissibility of protein misfolding diseasesAberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43)Evaluation of potential infectivity of Alzheimer and Parkinson disease proteins in recipients of cadaver-derived human growth hormone.Prion-like propagation of protein aggregation and related therapeutic strategies.Deciphering amyotrophic lateral sclerosis: what phenotype, neuropathology and genetics are telling us about pathogenesis.Stages of pTDP-43 pathology in amyotrophic lateral sclerosis.Evidence for prion-like mechanisms in several neurodegenerative diseases: potential implications for immunotherapyIn vitro prion-like behaviour of TDP-43 in ALS.
P2860
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P2860
A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@ast
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@en
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@nl
type
label
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@ast
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@en
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@nl
prefLabel
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@ast
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@en
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@nl
P2093
P2860
P3181
P356
P1476
A seeding reaction recapitulat ...... -binding protein-43 inclusions
@en
P2093
Kumi Kaneko
Nobuyuki Nukina
Shoji Watanabe
P2860
P304
18664-18672
P3181
P356
10.1074/JBC.M111.231209
P407
P577
2011-03-24T00:00:00Z