Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine. - Test2 - elhamkhani - TriplyDB

Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine.

Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine.

http://www.wikidata.org/entity/Q37336685

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Zyklophin, a systemically active selective kappa opioid receptor peptide antagonist with short duration of action Neurocircuitry of addiction Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction Animal studies of addictive behavior Stress and VTA synapses: implications for addiction and depression Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys.Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence The one-two punch of alcoholism: role of central amygdala dynorphins/kappa-opioid receptors The development and maintenance of drug addiction Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization.The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse Neurobiology of dysregulated motivational systems in drug addiction.Salvinorin A analogs and other κ-opioid receptor compounds as treatments for cocaine abuse.Convergent pharmacological mechanisms in impulsivity and addiction: insights from rodent models.Activation of the opioid μ1, but not δ or κ, receptors is required for nicotine reinforcement in a rat model of drug self-administration.Pharmacology and anti-addiction effects of the novel κ opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake.Mephedrone alters basal ganglia and limbic dynorphin systems.The dark side of emotion: the addiction perspective Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats.Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats.Compulsive-like responding for opioid analgesics in rats with extended access.The darkness within: individual differences in stress Early maternal separation affects ethanol-induced conditioning in a nor-BNI insensitive manner, but does not alter ethanol-induced locomotor activity Modulation of mood States as a major factor in relapse to substance use.A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behavior Relative Timing Between Kappa Opioid Receptor Activation and Cocaine Determines the Impact on Reward and Dopamine Release Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving.The macrocyclic tetrapeptide [D-Trp]CJ-15,208 produces short-acting κ opioid receptor antagonism in the CNS after oral administration.Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration.Acute withdrawal from chronic escalating-dose binge cocaine administration alters kappa opioid receptor stimulation of [35S] guanosine 5'-O-[gamma-thio]triphosphate acid binding in the rat ventral tegmental area.Addiction is a Reward Deficit and Stress Surfeit Disorder.Addiction as a stress surfeit disorder.Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake.Neurobiological mechanisms that contribute to stress-related cocaine use.The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking Preclinical evidence of new opioid modulators for the treatment of addiction.The dynorphin/κ-opioid receptor system and its role in psychiatric disorders.Psychiatric neural networks and neuropharmacology: Selected advances and novel implications

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Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine.

http://www.wikidata.org/entity/Q37336685

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 30 May 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Inhibition of kappa opioid rec ...... th extended access to cocaine.

@en

Inhibition of kappa opioid rec ...... th extended access to cocaine.

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type

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Inhibition of kappa opioid rec ...... th extended access to cocaine.

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Inhibition of kappa opioid rec ...... th extended access to cocaine.

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prefLabel

Inhibition of kappa opioid rec ...... th extended access to cocaine.

@en

Inhibition of kappa opioid rec ...... th extended access to cocaine.

@nl

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S00213-009-1563-Y

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Psychopharmacology

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Inhibition of kappa opioid rec ...... th extended access to cocaine.

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George F Koob

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John R Cashman

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Senait Ghirmai

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Sunmee Wee

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P2860

Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users

Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system

A role for brain stress systems in addiction.

The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking

Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats

Psychotomimesis mediated by kappa opiate receptors

Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens

Drug abuse: hedonic homeostatic dysregulation

Differentiation of kappa opioid agonist-induced antinociception by naltrexone apparent pA2 analysis in rhesus monkeys.

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10.1007/S00213-009-1563-Y

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