Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities - Test2 - elhamkhani - TriplyDB

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

http://www.wikidata.org/entity/Q24652603

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Emerging pharmacotherapies for neurodevelopmental disorders Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome Rett Syndrome: Crossing the Threshold to Clinical Translation Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders MECP2 disorders: from the clinic to mice and back Investigation of Rett syndrome using pluripotent stem cells Astrocytes conspire with neurons during progression of neurological disease The impact of MeCP2 loss- or gain-of-function on synaptic plasticity The molecular basis of cognitive deficits in pervasive developmental disorders GABA and glutamate pathways are spatially and developmentally affected in the brain of Mecp2-deficient mice Rett Syndrome: Reaching for Clinical Trials Molecular genetics of mouse serotonin neurons across the lifespan.A review of Rett syndrome (RTT) with induced pluripotent stem cells Rett syndrome: disruption of epigenetic control of postnatal neurological functions Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome Developmental expression of δ-opioid receptors during maturation of the parasympathetic, sympathetic, and sensory innervations of the neonatal heart: early targets for opioid regulation of autonomic control MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes Unexpected cellular players in Rett syndrome pathology Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome.Induced gamma oscillations differentiate familiar and novel voices in children with MECP2 duplication and Rett syndromes.Mild expression differences of MECP2 influencing aggressive social behavior.Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies.Beyond Widespread Mecp2 Deletions to Model Rett Syndrome: Conditional Spatio-Temporal Knockout, Single-Point Mutations and Transgenic Rescue Mice Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation.Improvement of the Rett syndrome phenotype in a MeCP2 mouse model upon treatment with levodopa and a dopa-decarboxylase inhibitor Biogenic amine metabolism in juvenile neurocardiogenic syncope with dysautonomia.Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons.Autonomic breathing abnormalities in Rett syndrome: caregiver perspectives in an international database study.Pinpointing brainstem mechanisms responsible for autonomic dysfunction in Rett syndrome: therapeutic perspectives for 5-HT1A agonists.Effect of Sarizotan, a 5-HT1a and D2-like receptor agonist, on respiration in three mouse models of Rett syndrome The neural circuit basis of Rett syndrome Neuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes.Methyl-CpG binding domain proteins inhibit interspecies courtship and promote aggression in Drosophila.Biogenic amines and their metabolites are differentially affected in the Mecp2-deficient mouse brain.β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome Pontine norepinephrine defects in Mecp2-null mice involve deficient expression of dopamine beta-hydroxylase but not a loss of catecholaminergic neurons.Is X-linked methyl-CpG binding protein 2 a new target for the treatment of Parkinson's disease Cell-autonomous alterations in dendritic arbor morphology and connectivity induced by overexpression of MeCP2 in Xenopus central neurons in vivo

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P2860

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

http://www.wikidata.org/entity/Q24652603

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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type

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Proceedings of the National Academy of Sciences of the United States of America

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Loss of MeCP2 in aminergic neu ...... cific behavioral abnormalities

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Alan Percy

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Caleigh Mandel-Brehm

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Christina Thaller

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Daniel G Glaze

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Hsiao-Tuan Chao

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Jun Ren

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Peter Humphreys

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Sharyl L Fyffe-Maricich

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P2860

The history of dopamine and levodopa in the treatment of Parkinson's disease

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

MeCP2, a key contributor to neurological disease, activates and represses transcription

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

The story of Rett syndrome: from clinic to neurobiology

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome

Defect in normal developmental increase of the brain biogenic amine concentrations in the mecp2-null mouse

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51

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40685131

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