A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
about
Anaplerotic triheptanoin diet enhances mitochondrial substrate use to remodel the metabolome and improve lifespan, motor function, and sociability in MeCP2-null miceCommon variants within MECP2 confer risk of systemic lupus erythematosusComparative study of methyl-CpG-binding domain proteinsAlterations of GABAergic signaling in autism spectrum disordersEpigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.The Ski protein family is required for MeCP2-mediated transcriptional repressionThe human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNAInteraction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardationA family of human zinc finger proteins that bind methylated DNA and repress transcriptionCDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndromeReduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndromeSpecific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus.CpG binding protein is crucial for early embryonic developmentT-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-siteExpression of MeCP2 in postmitotic neurons rescues Rett syndrome in miceThe p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressorRett syndrome and MeCP2: linking epigenetics and neuronal functionEmerging pharmacotherapies for neurodevelopmental disordersPathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndromeBioaminergic neuromodulation of respiratory rhythm in vitroMeCP2, a key contributor to neurological disease, activates and represses transcriptionPartial reversal of Rett Syndrome-like symptoms in MeCP2 mutant miceLoss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalitiesThe odyssey of MeCP2 and parental imprintingRett syndrome: clinical review and genetic updateDLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiencyCGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndromeModifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseEmerging Molecular and Biological Functions of MBD2, a Reader of DNA MethylationClinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Recent advances in understanding synaptic abnormalities in Rett syndromeCharacterizing autism spectrum disorders by key biochemical pathways.MECP2 disorders: from the clinic to mice and backThe "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNSDNA methylation in mammalsThe impact of MeCP2 loss- or gain-of-function on synaptic plasticityThe molecular basis of cognitive deficits in pervasive developmental disordersHow do immune cells support and shape the brain in health, disease, and aging?Abnormalities of the DNA methylation mark and its machinery: an emerging cause of neurologic dysfunction
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P2860
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
description
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2001
@ast
im März 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/03/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/03/01)
@nl
наукова стаття, опублікована в березні 2001
@uk
name
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@ast
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@en
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@nl
type
label
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@ast
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@en
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@nl
prefLabel
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@ast
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@en
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@nl
P2093
P3181
P356
P1433
P1476
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
@en
P2093
P2888
P304
P3181
P356
10.1038/85899
P407
P577
2001-03-01T00:00:00Z