Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation
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The expression of the ubiquitin ligase subunit Cks1 in human breast cancerDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerRUNX3 has an oncogenic role in head and neck cancerCyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cellsThe APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exitConstitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancerWrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes.Information theoretical quantification of cooperativity in signalling complexes.Roles of periostin in symptom manifestation and airway remodeling in a murine model of allergic rhinitisIdentification of SCF ubiquitin ligase substrates by global protein stability profiling.ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancerAberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death.CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.Prospects of RNA interference therapy for cancer.Prognostic role of p27Kip1 deregulation in colorectal cancer.Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative diseaseUbiquitin ligases in cancer: ushers for degradation.Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer.Cks1 enhances transcription efficiency at the GAL1 locus by linking the Paf1 complex to the 19S proteasomeLoss of cks1 homeostasis deregulates cell division cycle.Epidermal growth factor upregulates Skp2/Cks1 and p27(kip1) in human extrahepatic cholangiocarcinoma cellsCks1: Structure, Emerging Roles and Implications in Multiple CancersGrowth and progression of melanoma and non-melanoma skin cancers regulated by ubiquitination.Immunohistochemical evaluation of oral epithelial dysplasia using cyclin-D1, p27 and p63 expression as predictors of malignant transformation.p27(Kip1) expression as a prognostic marker for squamous cell carcinoma of the head and neck.Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report.NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers.Skp2 is an independent prognosticator of gallbladder carcinoma among p27(Kip1)-interacting cell cycle regulators: an immunohistochemical study of 62 cases by tissue microarray.Growth suppression induced by Notch1 activation involves Wnt-beta-catenin down-regulation in human tongue carcinoma cells.Clinicopathologic implications of the miR-197/PD-L1 axis in oral squamous cell carcinomaOverexpression of CDC28 protein kinase regulatory subunit 1B confers an independent prognostic factor in nasopharyngeal carcinoma.CKS1 expression in melanocytic nevi and melanoma.Cumulative alterations of p27-related cell-cycle regulators in the development of endometriosis-associated ovarian clear cell adenocarcinoma.CKS1B overexpression implicates clinical aggressiveness of hepatocellular carcinomas but not p27(Kip1) protein turnover: an independent prognosticator with potential p27 (Kip1)-independent oncogenic attributes?
P2860
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P2860
Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@ast
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@en
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@nl
type
label
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@ast
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@en
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@nl
prefLabel
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@ast
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@en
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@nl
P2093
P2860
P1476
Role of Cks1 overexpression in ...... 2 in promoting p27 degradation
@en
P2093
Ikuko Ogawa
Masae Kitagawa
Mutsumi Miyauchi
Shojiro Kitajima
Takashi Takata
Tarig Bashir
Yasusei Kudo
P2860
P304
P356
10.1016/S0002-9440(10)63264-6
P407
P577
2004-12-01T00:00:00Z