Furin at the cutting edge: from protein traffic to embryogenesis and disease
about
Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelinTrafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulationThe proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modificationsA PACS-1, GGA3 and CK2 complex regulates CI-MPR traffickingThe cargo receptor p24A facilitates calcium sensing receptor maturation and stabilization in the early secretory pathwayProprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi networkStructure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transportersCell-surface processing of pro-ADAMTS9 by furinFurin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytesBeta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furinFunctional consequences of the subdomain organization of the sulfsCleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infectionTrafficking of vesicular neurotransmitter transportersComputational prediction of furin cleavage sites by a hybrid method and understanding mechanism underlying diseasesThe phosphorylation state of an autoregulatory domain controls PACS-1-directed protein trafficSoluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR siteCripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturationNeogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membraneT-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune toleranceAlternative Antigen Processing for MHC Class I: Multiple Roads Lead to RomeBlood pressure and amiloride-sensitive sodium channels in vascular and renal cellsThe BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation.The herpes virus Fc receptor gE-gI mediates antibody bipolar bridging to clear viral antigens from the cell surfaceBunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidaseCleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinaseUnexpected similarity between the cytosolic West Nile virus NS3 and the secretory furin-like serine proteinasesStructures of immature flavivirus particlesCleavage preference distinguishes the two-component NS2B–NS3 serine proteinases of Dengue and West Nile virusesExpression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B–NS3 junction regionSwitching the Substrate Specificity of the Two-Component NS2B-NS3 Flavivirus Proteinase by Structure-Based MutagenesisCharacterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking.Differential Modulation of prM Cleavage, Extracellular Particle Distribution, and Virus Infectivity by Conserved Residues at Nonfurin Consensus Positions of the Dengue Virus pr-M JunctionDifferential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2Structural Basis for Dual-Inhibition Mechanism of a Non-Classical Kazal-Type Serine Protease Inhibitor from Horseshoe Crab in Complex with SubtilisinDomain Flexibility Modulates the Heterogeneous Assembly Mechanism of Anthrax Toxin Protective AntigenX-ray Structures of Human Furin in Complex with Competitive InhibitorsAn ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse modelNovel Furin Inhibitors with Potent Anti-infectious ActivityStepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ.Oral Delivery of Protein Drugs Bioencapsulated in Plant Cells
P2860
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P2860
Furin at the cutting edge: from protein traffic to embryogenesis and disease
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@ast
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@en
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@nl
type
label
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@ast
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@en
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@nl
altLabel
Furin at the cutting edge: From protein traffic to embryogenesis and disease
@en
prefLabel
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@ast
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@en
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@nl
P2860
P3181
P356
P1476
Furin at the cutting edge: from protein traffic to embryogenesis and disease
@en
P2093
Gary Thomas
P2860
P2888
P304
P3181
P356
10.1038/NRM934
P407
P577
2002-10-01T00:00:00Z
P5875
P6179
1024352145