Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy
about
Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domainsMyokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channelNew molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsAKAP150 signaling complex promotes suppression of the M-current by muscarinic agonistsProtein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activityControl of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase.Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis.Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy.Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit.Is there a role for potassium channel openers in neuronal ion channel disorders?Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels.Voltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration.Potassium channels: how genetic studies of epileptic syndromes open paths to new therapeutic targets and drugs.A Gly98Val mutation in the N-Myc downstream regulated gene 1 (NDRG1) in Alaskan Malamutes with polyneuropathyThe neuronal channelopathies.Made for "anchorin": Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons.Contributions of Kv7-mediated potassium current to sub- and suprathreshold responses of rat layer II/III neocortical pyramidal neurons.Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine.Excitatory muscarinic modulation strengthens virtual nicotinic synapses on sympathetic neurons and thereby enhances synaptic gainMolecular microdomains in a sensory terminal, the vestibular calyx endingMolecular basis of Mendelian idiopathic epilepsies.Genetics of idiopathic generalized epilepsies.Epilepsy: a review of selected clinical syndromes and advances in basic science.Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers.Coupling of L-type Ca2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity.Nervous system KV7 disorders: breakdown of a subthreshold brake.Activation of neuronal Kv7/KCNQ/M-channels by the opener QO58-lysine and its anti-nociceptive effects on inflammatory pain in rodents.A KCNQ channel opener for experimental neonatal seizures and status epilepticusInvolvement of cortical fast-spiking parvalbumin-positive basket cells in epilepsy.Distinct enzyme combinations in AKAP signalling complexes permit functional diversity.New tricks for old dogs: KCNQ expression and role in smooth muscle.Distribution of M-channel subunits KCNQ2 and KCNQ3 in rat hippocampusPharmacological modulation of the voltage-gated neuronal Kv7/KCNQ/M-channel alters the intrinsic excitability and synaptic responses of pyramidal neurons in rat prefrontal cortex slices.Differential Regulation of PI(4,5)P2 Sensitivity of Kv7.2 and Kv7.3 Channels by Calmodulin.Modulation of Kv7 channels and excitability in the brain.The C-terminal domain of ßIV-spectrin is crucial for KCNQ2 aggregation and excitability at nodes of Ranvier.Modulation of ERG channels by XE991.Ionic permeation and conduction properties of neuronal KCNQ2/KCNQ3 potassium channels.Orchestration of "presto" and "largo" synchrony in up-down activity of cortical networks
P2860
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P2860
Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy
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2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
Colocalization and coassembly ...... s that are mutated in epilepsy
@ast
Colocalization and coassembly ...... s that are mutated in epilepsy
@en
Colocalization and coassembly ...... s that are mutated in epilepsy
@nl
type
label
Colocalization and coassembly ...... s that are mutated in epilepsy
@ast
Colocalization and coassembly ...... s that are mutated in epilepsy
@en
Colocalization and coassembly ...... s that are mutated in epilepsy
@nl
prefLabel
Colocalization and coassembly ...... s that are mutated in epilepsy
@ast
Colocalization and coassembly ...... s that are mutated in epilepsy
@en
Colocalization and coassembly ...... s that are mutated in epilepsy
@nl
P2093
P2860
P356
P1476
Colocalization and coassembly ...... s that are mutated in epilepsy
@en
P2093
E C Cooper
K D Aldape
M S Berger
N M Barbaro
W S Peacock
P2860
P304
P356
10.1073/PNAS.090092797
P407
P577
2000-04-25T00:00:00Z