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Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

http://www.wikidata.org/entity/Q29615757

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Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer Human genetics and genomics a decade after the release of the draft sequence of the human genome Cancer genome landscapes Epigenetic modifications in cancer ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2 Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes Metabolism of kidney cancer: from the lab to clinical practice Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers International network of cancer genome projects.Network of Cancer Genes (NCG 3.0): integration and analysis of genetic and network properties of cancer genes The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma State of the science: an update on renal cell carcinoma Massive genomic rearrangement acquired in a single catastrophic event during cancer development The Impact of External Factors on the Epigenome: In Utero and over Lifetime Epigenomics of clear cell renal cell carcinoma: mechanisms and potential use in molecular pathology Epigenetic modulators, modifiers and mediators in cancer aetiology and progression Targeting EZH2 in cancer Serine, glycine and one-carbon units: cancer metabolism in full circle Decade in review-kidney cancer: discoveries, therapies and opportunities New developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in glioma Recent progress toward epigenetic therapies: the example of mixed lineage leukemia Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumors Kidney cancer Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention Myeloid malignancies: mutations, models and management New insights and challenges in mismatch repair: getting over the chromatin hurdle Emerging patterns of somatic mutations in cancer Evolution of the cancer genome HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression Histone deacetylase inhibitors and epigenetic modifications as a novel strategy in renal cell carcinoma Cancer immunotherapy Inhibition of endogenous hydrogen sulfide production in clear-cell renal cell carcinoma cell lines and xenografts restricts their growth, survival and angiogenic potential.The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

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P2860

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

http://www.wikidata.org/entity/Q29615757

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

@ast

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

@en

type

label

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

@ast

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

@en

prefLabel

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

@ast

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

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Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

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Adam Butler

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Arjunan Rajasingham

http://www.w3.org/2001/XMLSchema#string

Bill Wondergem

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Catherine Leroy

http://www.w3.org/2001/XMLSchema#string

Chai Yin Kok

http://www.w3.org/2001/XMLSchema#string

Chris Greenman

http://www.w3.org/2001/XMLSchema#string

Claire Hardy

http://www.w3.org/2001/XMLSchema#string

Dave Beare

http://www.w3.org/2001/XMLSchema#string

David J McBride

http://www.w3.org/2001/XMLSchema#string

David Jones

http://www.w3.org/2001/XMLSchema#string

P2860

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

An integrated genomic analysis of human glioblastoma multiforme

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding

Patterns of somatic mutation in human cancer genomes

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

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360-363

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855161

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10.1038/NATURE08672

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7279

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463

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Tatiana Mironenko

Gillian L Dalgliesh

P Andrew Futreal

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2010-01-06T00:00:00Z

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40870204

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1032969139

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20054297

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2820242

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