Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions - Test2 - elhamkhani - TriplyDB

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

http://www.wikidata.org/entity/Q26269963

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Dopamine release in the basal ganglia The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia Unconventional secretion of synuclein-γ promotes tumor cell invasion Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro Secondary structure and dynamics of micelle bound beta- and gamma-synuclein Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2 Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein.Mouse Genetic Models of Human Brain Disorders Dynamic structural flexibility of α-synuclein Is Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson's Disease?Biophysical characterization of α-synuclein and its controversial structure Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticity Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease Synucleins antagonize endoplasmic reticulum function to modulate dopamine transporter trafficking A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.NMR Structure of Calmodulin Complexed to an N-Terminally Acetylated α-Synuclein Peptide The Synaptic Function of α-Synuclein The contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's disease Alpha-Synuclein in Parkinson's Disease: From Pathogenetic Dysfunction to Potential Clinical Application Genetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implications Gene-environment interactions: key to unraveling the mystery of Parkinson's disease αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction Investigation of intramolecular dynamics and conformations of α-, β- and γ-synuclein Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein Localization of synucleins in the mammalian cochlea {alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics.Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins.Genetic mouse models of parkinsonism: strengths and limitations.Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes.ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Proteomic identification of novel substrates of a protein isoaspartyl methyltransferase repair enzyme.Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease.DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze?

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Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

http://www.wikidata.org/entity/Q26269963

description

2004 nî lūn-bûn

@nan

2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@ast

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@en

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@nl

type

label

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@ast

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@en

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@nl

prefLabel

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@ast

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

@en

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

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Proceedings of the National Academy of Sciences of the United States of America

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Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

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Dwight C German

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Hyung-Bae Kwon

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Robert E Hammer

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Sreeganga Chandra

http://www.w3.org/2001/XMLSchema#string

Umar Yazdani

http://www.w3.org/2001/XMLSchema#string

Xinran Liu

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P2860

Complexins: cytosolic proteins that regulate SNAP receptor function

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

alpha-Synuclein locus triplication causes Parkinson's disease

Alpha-synuclein in Lewy bodies

alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

Peripheral nervous system-specific genes identified by subtractive cDNA cloning

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41

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101

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Giuseppe Battaglia

Pablo E Castillo

Francesco Fornai

Thomas C. Südhof

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8249562

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15465911

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Synuclein, alpha

Synuclein, beta

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522043

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