Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
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Dopamine release in the basal gangliaThe synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementiaUnconventional secretion of synuclein-γ promotes tumor cell invasionAlpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recyclingMutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodiesMitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synucleinAlpha-synuclein promotes SNARE-complex assembly in vivo and in vitroSecondary structure and dynamics of micelle bound beta- and gamma-synucleinProtein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseasesNative α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein.Mouse Genetic Models of Human Brain DisordersDynamic structural flexibility of α-synucleinIs Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson's Disease?Biophysical characterization of α-synuclein and its controversial structureAdult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticityFeatures of alpha-synuclein that could explain the progression and irreversibility of Parkinson's diseaseSynucleins antagonize endoplasmic reticulum function to modulate dopamine transporter traffickingA53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old miceParkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.NMR Structure of Calmodulin Complexed to an N-Terminally Acetylated α-Synuclein PeptideThe Synaptic Function of α-SynucleinThe contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's diseaseAlpha-Synuclein in Parkinson's Disease: From Pathogenetic Dysfunction to Potential Clinical ApplicationGenetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implicationsGene-environment interactions: key to unraveling the mystery of Parkinson's diseaseαβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunctionInvestigation of intramolecular dynamics and conformations of α-, β- and γ-synucleinTargeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's diseaseIncreased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synucleinLocalization of synucleins in the mammalian cochlea{alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics.Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins.Genetic mouse models of parkinsonism: strengths and limitations.Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes.ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Proteomic identification of novel substrates of a protein isoaspartyl methyltransferase repair enzyme.Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease.DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze?
P2860
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P2860
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@ast
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@en
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@nl
type
label
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@ast
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@en
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@nl
prefLabel
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@ast
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@en
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions
@en
P2093
Dwight C German
Hyung-Bae Kwon
Robert E Hammer
Sreeganga Chandra
Umar Yazdani
Xinran Liu
P2860
P304
P3181
P356
10.1073/PNAS.0406283101
P407
P577
2004-10-12T00:00:00Z