The amyloid hypothesis of Alzheimer's disease at 25 years
about
Amyloidosis in Retinal Neurodegenerative DiseasesAlzheimer's disease: the silver tsunami of the 21(st) centuryProteomic Substrate Identification for Membrane Proteases in the Brain3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish"Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's diseaseNumerical Simulations Reveal Randomness of Cu(II) Induced Aβ Peptide Dimerization under Conditions Present in Glutamatergic SynapsesGlutaminyl cyclase activity correlates with levels of Aβ peptides and mediators of angiogenesis in cerebrospinal fluid of Alzheimer's disease patients.Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril.Direct imaging of APP proteolysis in living cells.An Overview of the Protective Effects of Chitosan and Acetylated Chitosan Oligosaccharides against Neuronal Disorders.An intranasally delivered peptide drug ameliorates cognitive decline in Alzheimer transgenic mice.Quantification of Butyrylcholinesterase Activity as a Sensitive and Specific Biomarker of Alzheimer's Disease.The Anti-Inflammatory Effects of Lipoxygenase and Cyclo-Oxygenase Inhibitors in Inflammation-Induced Human Fetal Glia Cells and the Aβ Degradation Capacity of Human Fetal Astrocytes in an Ex vivo AssayNeuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease.Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Cell signalling pathway regulation by RanBPM: molecular insights and disease implications.Protein homeostasis of a metastable subproteome associated with Alzheimer's disease.Drug candidates in clinical trials for Alzheimer's disease.Region-Specific Differences in Amyloid Precursor Protein Expression in the Mouse Hippocampus.Alzheimer's amyloid-β A2T variant and its N-terminal peptides inhibit amyloid-β fibrillization and rescue the induced cytotoxicity.Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer's Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical DataExposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans.Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.Functions of the Alzheimer's Disease Protease BACE1 at the Synapse in the Central Nervous System.Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1.Yi-Zhi-Fang-Dai Formula Protects against Aβ1-42 Oligomer Induced Cell Damage via Increasing Hsp70 and Grp78 Expression in SH-SY5Y CellsAlzheimer-related protein APL-1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans.Human Neural Stem Cell Transplantation Rescues Cognitive Defects in APP/PS1 Model of Alzheimer's Disease by Enhancing Neuronal Connectivity and Metabolic ActivityCited references and Medical Subject Headings (MeSH) as two different knowledge representations: clustering and mappings at the paper level.Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's diseaseMT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitroNutrition and AGE-ing: Focusing on Alzheimer's Disease.Presenilin-1 mutations and Alzheimer's disease.Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of Aβ42 and Aβ40 peptides by γ-secretase.Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer's Therapy?Cerebrospinal Fluid Levels of Amyloid Beta 1-43 Mirror 1-42 in Relation to Imaging Biomarkers of Alzheimer's Disease.Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production.Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer's disease.Amyloid-beta immunotherapy: the hope for Alzheimer disease?Neuroprotective effect of the Chinese medicine Tiantai No. 1 and its molecular mechanism in the senescence-accelerated mouse prone 8
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P2860
The amyloid hypothesis of Alzheimer's disease at 25 years
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
The amyloid hypothesis of Alzheimer's disease at 25 years
@ast
The amyloid hypothesis of Alzheimer's disease at 25 years
@en
The amyloid hypothesis of Alzheimer's disease at 25 years
@nl
type
label
The amyloid hypothesis of Alzheimer's disease at 25 years
@ast
The amyloid hypothesis of Alzheimer's disease at 25 years
@en
The amyloid hypothesis of Alzheimer's disease at 25 years
@nl
prefLabel
The amyloid hypothesis of Alzheimer's disease at 25 years
@ast
The amyloid hypothesis of Alzheimer's disease at 25 years
@en
The amyloid hypothesis of Alzheimer's disease at 25 years
@nl
P2860
P921
P3181
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P1476
The amyloid hypothesis of Alzheimer's disease at 25 years
@en
P2093
Dennis J Selkoe
P2860
P304
P3181
P356
10.15252/EMMM.201606210
P407
P5008
P577
2016-06-01T00:00:00Z