about
Modulation of Protein-Protein Interactions for the Development of Novel TherapeuticsNOD-Like Receptors: Master Regulators of Inflammation and CancerHeat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesisSmall-molecule inhibitors of protein-protein interactions: progressing toward the reality.Lipid-conjugated Smac analogues.USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents.Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapantUSP11: A key regulator of cIAP2 stability and sensitivity to SMAC mimeticsAPRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment.Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide.X-linked inhibitor of apoptosis protein deficiency: more than an X-linked lymphoproliferative syndrome.Characterization of Somatically-Eliminated Genes During Development of the Sea Lamprey (Petromyzon marinus).Small molecule inhibitor of apoptosis proteins antagonists: a patent review.Landscape review of current HIV 'kick and kill' cure research - some kicking, not enough killing.RGD-mediated delivery of small-molecule drugs.The SMAC mimetic BV6 induces cell death and sensitizes different cell lines to TNF-α and TRAIL-induced apoptosis.Cancer therapies in HIV cure research.Impact of inhibitor of apoptosis proteins on immune modulation and inflammation.Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with Deregulation of Extrinsic and Intrinsic Cell Death Pathways.Exploiting poly(I:C) to induce cancer cell apoptosis.Improvement of Pharmacokinetic Profile of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo.The Interplay between Radioresistant Caco-2 Cells and the Immune System Increases Epithelial Layer Permeability and Alters Signaling Protein Spectrum.Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway.A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.Recurring Amplification at 11q22.1-q22.2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC.Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway.MOMP, cell suicide as a BCL-2 family business.Intracellular apoptotic pathways: a potential target for reducing joint damage in rheumatoid arthritis.Getting the "Kill" into "Shock and Kill": Strategies to Eliminate Latent HIV.Inhibitors of Apoptosis Protein Antagonists (Smac Mimetic Compounds) Control Polarization of Macrophages during Microbial Challenge and Sterile Inflammatory Responses.Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer.Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells.Combination of a Latency-Reversing Agent With a Smac Mimetic Minimizes Secondary HIV-1 InfectionMutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Small-molecule SMAC mimetics as new cancer therapeutics
@ast
Small-molecule SMAC mimetics as new cancer therapeutics
@en
Small-molecule SMAC mimetics as new cancer therapeutics
@nl
type
label
Small-molecule SMAC mimetics as new cancer therapeutics
@ast
Small-molecule SMAC mimetics as new cancer therapeutics
@en
Small-molecule SMAC mimetics as new cancer therapeutics
@nl
prefLabel
Small-molecule SMAC mimetics as new cancer therapeutics
@ast
Small-molecule SMAC mimetics as new cancer therapeutics
@en
Small-molecule SMAC mimetics as new cancer therapeutics
@nl
P2860
P1476
Small-molecule SMAC mimetics as new cancer therapeutics
@en
P2093
Longchuan Bai
P2860
P356
10.1016/J.PHARMTHERA.2014.05.007
P407
P577
2014-05-16T00:00:00Z